Guanylate kinase

NameGuanylate kinase
Synonyms
  • 2.7.4.8
  • GMP kinase
Gene Namegmk
OrganismMycobacterium tuberculosis
Amino acid sequence
>lcl|BSEQ0051155|Guanylate kinase
MSVGEGPDTKPTARGQPAAVGRVVVLSGPSAVGKSTVVRCLRERIPNLHFSVSATTRAPR
PGEVDGVDYHFIDPTRFQQLIDQGELLEWAEIHGGLHRSGTLAQPVRAAAATGVPVLIEV
DLAGARAIKKTMPEAVTVFLAPPSWQDLQARLIGRGTETADVIQRRLDTARIELAAQGDF
DKVVVNRRLESACAELVSLLVGTAPGSP
Number of residuesNone
Molecular Weight22095.065
Theoretical pINone
GO Classification
Functions
  • ATP binding
  • adenylate kinase activity
  • magnesium ion binding
  • guanylate kinase activity
  • GDP binding
  • GMP binding
Processes
  • growth
Components
  • cytosol
General FunctionEssential for recycling GMP and indirectly, cGMP.
Specific FunctionAdenylate kinase activity
Transmembrane Regions
GenBank Protein ID
UniProtKB IDP9WKE9
UniProtKB Entry Name
Cellular LocationCytoplasm
Gene sequence
>lcl|BSEQ0051156|Guanylate kinase (gmk)
GTGAGCGTCGGCGAGGGACCGGACACCAAGCCCACCGCGCGTGGCCAACCGGCGGCAGTG
GGACGTGTGGTGGTGCTGTCCGGTCCTTCCGCGGTCGGCAAATCCACGGTGGTTCGGTGT
CTGCGCGAGCGGATCCCGAATCTGCATTTCAGTGTCTCGGCCACGACGCGGGCGCCACGC
CCGGGCGAGGTCGACGGTGTCGACTACCACTTCATCGACCCCACCCGCTTTCAGCAGCTC
ATCGACCAGGGTGAGTTGCTGGAATGGGCAGAAATCCACGGCGGCCTGCACCGGTCGGGC
ACTTTGGCCCAGCCGGTGCGGGCGGCCGCGGCGACTGGTGTGCCGGTGCTTATCGAGGTT
GACCTGGCCGGGGCCAGGGCGATCAAGAAGACGATGCCCGAGGCTGTCACCGTGTTTCTG
GCGCCACCTAGCTGGCAGGATCTTCAGGCCAGACTGATTGGCCGCGGCACCGAAACAGCT
GACGTTATCCAACGCCGCCTGGACACCGCGCGGATCGAATTGGCAGCGCAGGGCGACTTT
GACAAGGTCGTGGTGAACAGGCGATTAGAGTCTGCGTGTGCGGAATTGGTATCCTTGCTG
GTGGGAACGGCACCGGGCTCCCCGTGA
GenBank Gene ID
GeneCard IDNone
GenAtlas ID
HGNC ID
Chromosome LocationNone
LocusNone
References
  1. Cole ST, Brosch R, Parkhill J, Garnier T, Churcher C, Harris D, Gordon SV, Eiglmeier K, Gas S, Barry CE 3rd, Tekaia F, Badcock K, Basham D, Brown D, Chillingworth T, Connor R, Davies R, Devlin K, Feltwell T, Gentles S, Hamlin N, Holroyd S, Hornsby T, Jagels K, Krogh A, McLean J, Moule S, Murphy L, Oliver K, Osborne J, Quail MA, Rajandream MA, Rogers J, Rutter S, Seeger K, Skelton J, Squares R, Squares S, Sulston JE, Taylor K, Whitehead S, Barrell BG: Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature. 1998 Jun 11;393(6685):537-44. [9634230 ]
  2. Kelkar DS, Kumar D, Kumar P, Balakrishnan L, Muthusamy B, Yadav AK, Shrivastava P, Marimuthu A, Anand S, Sundaram H, Kingsbury R, Harsha HC, Nair B, Prasad TS, Chauhan DS, Katoch K, Katoch VM, Kumar P, Chaerkady R, Ramachandran S, Dash D, Pandey A: Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry. Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3. [21969609 ]

From www.t3db.ca