Catalase

Name	Catalase
Synonyms	1.11.1.6
Gene Name	katA
Organism	Helicobacter pylori (strain ATCC 700392 / 26695)
Amino acid sequence	>lcl\|BSEQ0011880\|Catalase MVNKDVKQTTAFGAPVWDDNNVITAGPRGPVLLQSTWFLEKLAAFDRERIPERVVHAKGS GAYGTFTVTKDITKYTKAKIFSKVGKKTECFFRFSTVAGERGSADAVRDPRGFAMKYYTE EGNWDLVGNNTPVFFIRDAIKFPDFIHTQKRDPQTNLPNHDMVWDFWSNVPESLYQVTWV MSDRGIPKSFRHMDGFGSHTFSLINAKGERFWVKFHFHTMQGVKHLTNEEAAEVRKYDPD SNQRDLFNAIARGDFPKWKLSIQVMPEEDAKKYRFHPFDVTKIWYLQDYPLMEVGIVELN KNPENYFAEVEQAAFSPANVVPGIGYSPDRMLQGRLFSYGDTHRYRLGVNYPQIPVNKPR CPFHSSSRDGYMQNGYYGSLQNYTPSSLPGYKEDKSARDPKFNLAHIEKEFEVWNWDYRA DDSDYYTQPGDYYRSLPADEKERLHDTIGESLAHVTHKEIVDKQLEHFKKADPKYAEGVK KALEKHQKMMKDMHGKDMHHTKKKK
Number of residues	None
Molecular Weight	58628.85
Theoretical pI	9.04
GO Classification	Functions heme binding catalase activity metal ion binding Processes response to oxidative stress hydrogen peroxide catabolic process Components cytoplasm
General Function	Metal ion binding
Specific Function	Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
Transmembrane Regions
GenBank Protein ID
UniProtKB ID	P77872
UniProtKB Entry Name
Cellular Location	Cytoplasm
Gene sequence	>lcl\|BSEQ0011881\|Catalase (katA) ATGGTTAATAAAGATGTGAAACAAACCACTGCTTTTGGCGCTCCCGTTTGGGATGACAAC AATGTGATTACGGCCGGCCCTAGAGGTCCTGTTTTATTACAAAGCACTTGGTTTTTGGAA AAGTTAGCGGCGTTTGACAGAGAAAGAATCCCTGAAAGGGTGGTGCATGCTAAAGGAAGC GGAGCTTATGGCACTTTCACTGTGACTAAAGACATCACTAAATACACTAAAGCGAAAATT TTCTCTAAAGTGGGCAAAAAAACCGAATGCTTCTTCAGATTTTCTACTGTGGCTGGTGAA AGAGGCAGTGCGGATGCGGTGAGAGACCCTAGAGGTTTTGCGATGAAGTATTACACTGAA GAAGGTAACTGGGATTTAGTGGGGAACAACACGCCTGTTTTCTTTATCCGTGATGCGATC AAATTCCCTGATTTCATCCACACTCAAAAACGAGATCCTCAAACCAATTTGCCTAACCAT GACATGGTATGGGATTTTTGGAGTAATGTTCCTGAAAGCTTATACCAAGTAACATGGGTT ATGAGCGATAGGGGTATTCCTAAATCTTTCCGCCACATGGATGGTTTTGGCAGCCACACT TTCAGTCTTATCAACGCGAAAGGCGAACGCTTTTGGGTGAAATTCCACTTTCACACCATG CAAGGCGTTAAGCATTTGACTAACGAAGAAGCCGCAGAAGTTAGGAAGTATGATCCGGAT TCCAATCAAAGGGATTTATTCAATGCGATCGCTAGAGGGGATTTCCCAAAATGGAAATTA AGCATTCAAGTGATGCCAGAAGAAGATGCTAAGAAGTATCGATTCCATCCGTTTGATGTA ACTAAAATTTGGTATCTCCAAGATTATCCATTGATGGAAGTGGGCATTGTGGAGTTGAAT AAAAATCCTGAAAACTATTTCGCAGAAGTGGAACAAGCGGCATTCAGTCCGGCTAATGTC GTTCCTGGAATTGGCTATAGCCCTGATAGGATGTTACAAGGGCGCTTGTTCTCTTATGGA GACACACACCGCTACCGCTTAGGCGTTAATTATCCTCAAATACCGGTTAATAAACCAAGA TGCCCATTCCACTCTTCTAGCAGAGATGGTTACATGCAAAACGGATACTACGGCTCTTTA CAAAACTATACGCCTAGCTCATTGCCTGGCTATAAAGAAGATAAGAGCGCGAGAGATCCT AAGTTCAACTTAGCTCATATTGAGAAAGAGTTTGAAGTGTGGAATTGGGATTACAGAGCT GATGATAGCGATTACTACACCCAACCAGGTGATTACTACCGCTCATTGCCAGCTGATGAA AAAGAAAGGTTGCATGACACTATTGGAGAGTCTTTAGCTCATGTTACCCATAAGGAAATT GTGGATAAACAATTGGAGCATTTCAAGAAAGCTGACCCCAAATACGCTGAGGGAGTTAAA AAAGCTCTTGAAAAACACCAAAAAATGATGAAAGACATGCATGGAAAAGACATGCACCAC ACAAAAAAGAAAAAGTAA
GenBank Gene ID
GeneCard ID	None
GenAtlas ID
HGNC ID
Chromosome Location	None
Locus	None
References	Manos J, Kolesnikow T, Hazell SL: An investigation of the molecular basis of the spontaneous occurrence of a catalase-negative phenotype in Helicobacter pylori. Helicobacter. 1998 Mar;3(1):28-38. [9546115 ] Odenbreit S, Wieland B, Haas R: Cloning and genetic characterization of Helicobacter pylori catalase and construction of a catalase-deficient mutant strain. J Bacteriol. 1996 Dec;178(23):6960-7. [8955320 ] Tomb JF, White O, Kerlavage AR, Clayton RA, Sutton GG, Fleischmann RD, Ketchum KA, Klenk HP, Gill S, Dougherty BA, Nelson K, Quackenbush J, Zhou L, Kirkness EF, Peterson S, Loftus B, Richardson D, Dodson R, Khalak HG, Glodek A, McKenney K, Fitzegerald LM, Lee N, Adams MD, Hickey EK, Berg DE, Gocayne JD, Utterback TR, Peterson JD, Kelley JM, Cotton MD, Weidman JM, Fujii C, Bowman C, Watthey L, Wallin E, Hayes WS, Borodovsky M, Karp PD, Smith HO, Fraser CM, Venter JC: The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature. 1997 Aug 7;388(6642):539-47. [9252185 ]

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