Ribosomal small subunit pseudouridine synthase A

NameRibosomal small subunit pseudouridine synthase A
Synonyms
  • 16S pseudouridylate 516 synthase
  • 16S rRNA pseudouridine(516) synthase
  • 5.4.99.19
  • rRNA pseudouridylate synthase A
  • rRNA-uridine isomerase A
Gene NamersuA
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Amino acid sequence
>lcl|BSEQ0019089|Ribosomal small subunit pseudouridine synthase A
MRLDKFIAENVGLTRSQATKAIRQSAVKINGEIVKSGSVQISQEDEIYFEDELLTWIEEG
QYFMLNKPQGCVCSNDDGDYPTIYQFFDYPLAGKLHSAGRLDVDTTGLVLLTDDGQWSHR
ITSPKHHCEKTYLVTLADPVEENYSAACAEGILLRGEKEPTKPAKLEILDDYNVNLTISE
GRYHQVKRMFAALGNKVVGLHRWKIGDVVLDESLEEGEYRPLTQSEIEKLVK
Number of residuesNone
Molecular Weight26212.405
Theoretical pI4.75
GO Classification
Functions
  • RNA binding
  • pseudouridine synthase activity
Processes
  • rRNA processing
  • pseudouridine synthesis
Components
General FunctionRna binding
Specific FunctionResponsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA.
Transmembrane Regions
GenBank Protein ID
UniProtKB IDP45124
UniProtKB Entry Name
Cellular LocationCytoplasmic
Gene sequence
>lcl|BSEQ0019090|Ribosomal small subunit pseudouridine synthase A (rsuA)
ATGAGATTAGATAAATTTATTGCTGAAAATGTGGGATTAACTCGTTCTCAAGCAACAAAA
GCGATCCGCCAAAGTGCGGTAAAAATCAACGGTGAAATTGTCAAAAGTGGTTCGGTTCAA
ATTTCACAAGAAGACGAAATTTATTTTGAAGATGAATTATTAACTTGGATCGAAGAAGGC
CAGTATTTTATGTTGAATAAACCACAAGGCTGTGTTTGTTCTAATGATGACGGCGACTAT
CCAACAATTTATCAATTTTTTGATTACCCTTTAGCTGGAAAATTACATAGCGCAGGTCGC
TTAGATGTGGATACGACAGGTCTCGTATTGCTTACCGATGATGGACAATGGTCACATCGC
ATCACTTCCCCAAAGCATCATTGTGAAAAAACCTATTTGGTGACATTAGCTGATCCCGTA
GAAGAAAATTATTCAGCAGCTTGTGCAGAAGGCATTTTATTACGCGGAGAAAAAGAGCCC
ACTAAACCAGCAAAATTAGAAATTTTAGATGACTACAATGTGAATCTGACCATTTCTGAA
GGTCGTTATCATCAAGTAAAACGTATGTTTGCCGCACTTGGGAATAAAGTCGTTGGATTA
CATCGCTGGAAAATTGGTGATGTAGTGTTGGATGAATCCTTAGAAGAAGGCGAATACCGC
CCATTAACTCAAAGTGAAATTGAAAAGTTAGTAAAATAA
GenBank Gene ID
GeneCard IDNone
GenAtlas ID
HGNC ID
Chromosome LocationNone
LocusNone
References
  1. Fleischmann RD, Adams MD, White O, Clayton RA, Kirkness EF, Kerlavage AR, Bult CJ, Tomb JF, Dougherty BA, Merrick JM, et al.: Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. Science. 1995 Jul 28;269(5223):496-512. [7542800 ]
  2. Matte A, Louie GV, Sivaraman J, Cygler M, Burley SK: Structure of the pseudouridine synthase RsuA from Haemophilus influenzae. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Apr 1;61(Pt 4):350-4. Epub 2005 Mar 12. [16511038 ]

From www.t3db.ca