Phosphoserine aminotransferase

Name	Phosphoserine aminotransferase
Synonyms	2.6.1.52 Phosphohydroxythreonine aminotransferase PSAT
Gene Name	serC
Organism	Bacillus alcalophilus
Amino acid sequence	>lcl\|BSEQ0016875\|Phosphoserine aminotransferase MVKQVFNFNAGPSALPKPALERAQKELLNFNDTQMSVMELSHRSQSYEEVHEQAQNLLRE LLQIPNDYQILFLQGGASLQFTMLPMNLLTKGTIGNYVLTGSWSEKALKEAKLLGETHIA ASTKANSYQSIPDFSEFQLNENDAYLHITSNNTIYGTQYQNFPEINHAPLIADMSSDILS RPLKVNQFGMIYAGAQKNLGPSGVTVVIVKKDLLNTKVEQVPTMLQYATHIKSDSLYNTP PTFSIYMLRNVLDWIKDLGGAEAIAKQNEEKAKIIYDTIDESNGFYVGHAEKGSRSLMNV TFNLRNEELNQQFLAKAKEQGFVGLNGHRSVGGCRASIYNAVPIDACIALRELMIQFKEN A
Number of residues	None
Molecular Weight	40334.61
Theoretical pI	6.32
GO Classification	Functions pyridoxal phosphate binding O-phospho-L-serine Processes L-serine biosynthetic process Components cytoplasm
General Function	Pyridoxal phosphate binding
Specific Function	Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
Transmembrane Regions
GenBank Protein ID
UniProtKB ID	Q9RME2
UniProtKB Entry Name
Cellular Location	Cytoplasm
Gene sequence	>lcl\|BSEQ0005354\|1086 bp ATGGTAAAACAAGTTTTTAACTTTAATGCAGGTCCTTCCGCATTACCTAAACCAGCCTTA GAACGAGCACAAAAAGAATTGCTTAACTTTAACGATACTCAAATGTCTGTGATGGAATTA AGTCATCGTAGTCAAAGCTATGAGGAAGTTCATGAACAAGCTCAAAATTTATTACGTGAG CTCCTTCAAATCCCAAATGATTATCAAATATTATTCTTACAAGGTGGGGCGAGCTTACAA TTTACTATGTTACCAATGAACCTTTTAACAAAAGGAACCATTGGTAACTATGTGCTAACC GGTTCGTGGTCAGAAAAAGCTTTAAAAGAGGCTAAGCTTTTGGGTGAAACACATATAGCT GCCTCTACAAAAGCAAATAGTTACCAGAGCATCCCAGACTTTTCTGAATTCCAATTAAAC GAAAATGATGCTTATCTTCACATTACCTCAAATAACACGATTTACGGTACACAATATCAG AACTTTCCAGAGATAAATCACGCTCCACTTATCGCTGATATGTCAAGTGATATCTTATCT CGCCCACTTAAAGTCAATCAATTTGGAATGATTTATGCTGGGGCACAAAAGAACCTTGGA CCTTCAGGTGTTACAGTTGTTATCGTTAAGAAGGATTTACTCAATACCAAAGTAGAACAA GTTCCGACTATGCTACAATACGCAACTCATATAAAGTCAGATTCCCTTTATAATACCCCT CCTACATTTTCCATCTATATGCTTCGAAATGTATTGGATTGGATAAAGGATTTGGGTGGA GCGGAAGCAATCGCAAAACAAAATGAAGAAAAAGCCAAAATTATTTACGATACAATTGAT GAAAGTAATGGCTTTTATGTTGGTCACGCGGAAAAAGGAAGTCGCTCACTAATGAACGTT ACATTTAACTTGCGAAATGAAGAATTAAATCAACAGTTCTTAGCCAAAGCAAAGGAACAA GGTTTTGTCGGACTTAACGGCCACCGTTCAGTTGGAGGCTGTCGTGCTTCCATCTATAAT GCCGTGCCTATAGATGCTTGTATCGCTTTGCGAGAGCTAATGATTCAATTTAAAGAAAAC GCGTAA
GenBank Gene ID
GeneCard ID	None
GenAtlas ID
HGNC ID
Chromosome Location	None
Locus	None
References	Dubnovitsky AP, Kapetaniou EG, Papageorgiou AC: Expression, purification, crystallization and preliminary crystallographic analysis of phosphoserine aminotransferase from Bacillus alcalophilus. Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2319-21. Epub 2003 Nov 27. [14646107 ] Dubnovitsky AP, Kapetaniou EG, Papageorgiou AC: Enzyme adaptation to alkaline pH: atomic resolution (1.08 A) structure of phosphoserine aminotransferase from Bacillus alcalophilus. Protein Sci. 2005 Jan;14(1):97-110. [15608117 ] Dubnovitsky AP, Ravelli RB, Popov AN, Papageorgiou AC: Strain relief at the active site of phosphoserine aminotransferase induced by radiation damage. Protein Sci. 2005 Jun;14(6):1498-507. Epub 2005 May 9. [15883191 ]

From www.t3db.ca