EC number:1.1.1.111
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.111 |
|---|---|
| Description: | 3-(imidazol-5-yl)lactate dehydrogenase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.111 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.111 |
| KEGG Enzyme Link: | KEGG1.1.1.111 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.111 |
| ExPASy Enzyme Link: | ExPASy1.1.1.111 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.111 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.111 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.111 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.111 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.111 |
EC number:1.1.1.111
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:12040 | (S)-3-(imidazol-5-yl)lactate + NADP(+) = 3-(imidazol-5-yl)pyruvate + H(+) + NADPH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The role of imidazol-5-yl-lactate-nicotinamide-adenine dinucleotide phosphate oxidoreductase and histidine-2-oxoglutarate aminotransferase in the degradation of imidazol-5-yl-lactate by Pseudomonas acidovorans. | Coote JG, Hassall H | 1969 Jan | 4303364 |
| [Identification and purification of an alpha-ketoacid aromatic reductase of Escherichia coli B]. | Cortese R, Brevet J, Hedegaard J, Roche J | 1968 | 4237631 |
| RHEA:12036 | (S)-3-(imidazol-5-yl)lactate + NAD(+) = 3-(imidazol-5-yl)pyruvate + H(+) + NADH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The role of imidazol-5-yl-lactate-nicotinamide-adenine dinucleotide phosphate oxidoreductase and histidine-2-oxoglutarate aminotransferase in the degradation of imidazol-5-yl-lactate by Pseudomonas acidovorans. | Coote JG, Hassall H | 1969 Jan | 4303364 |
| [Identification and purification of an alpha-ketoacid aromatic reductase of Escherichia coli B]. | Cortese R, Brevet J, Hedegaard J, Roche J | 1968 | 4237631 |