EC number:1.1.1.18
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.18 |
|---|---|
| Description: | Inositol 2-dehydrogenase. |
| Alternative Name: |
Myo-inositol 2-dehydrogenase. |
| Cath: | 3.30.360.10; 3.40.50.720; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.18 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.18 |
| KEGG Enzyme Link: | KEGG1.1.1.18 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.18 |
| ExPASy Enzyme Link: | ExPASy1.1.1.18 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.18 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.18 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.18 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.18 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.18 |
| RHEA:16949 | myo-inositol + NAD(+) = H(+) + NADH + scyllo-inosose |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Structural investigation of myo-inositol dehydrogenase from Bacillus subtilis: implications for catalytic mechanism and inositol dehydrogenase subfamily classification. | van Straaten KE, Zheng H, Palmer DR, Sanders DA | 2010 Dec 1 | 20809899 |
| Purification, crystallization and preliminary X-ray analysis of inositol dehydrogenase (IDH) from Bacillus subtilis. | Van Straaten KE, Hoffort A, Palmer DR, Sanders DA | 2008 Feb 1 | 18259059 |
| Probing the promiscuous active site of myo-inositol dehydrogenase using synthetic substrates, homology modeling, and active site modification. | Daniellou R, Zheng H, Langill DM, Sanders DA, Palmer DR | 2007 Jun 26 | 17539607 |
| Identification of two scyllo-inositol dehydrogenases in Bacillus subtilis. | Morinaga T, Ashida H, Yoshida K | 2010 May | 20133360 |