EC number:1.1.1.196

Enzyme

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     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.196
Description:15-hydroxyprostaglandin-D dehydrogenase (NADP(+)).
Alternative Name: Prostaglandin-D 15-dehydrogenase (NADP+).
Prostaglandin-D 15-dehydrogenase (NADP(+)).
Cath: 3.40.50.720;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.196
BRENDA Enzyme Link: BRENDA 1.1.1.196
KEGG Enzyme Link: KEGG1.1.1.196
BioCyc Enzyme Link: BioCyc 1.1.1.196
ExPASy Enzyme Link: ExPASy1.1.1.196
EC2PDB Enzyme Link: EC2PDB 1.1.1.196
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.196
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.196
IntEnz Enzyme Link: IntEnz 1.1.1.196
MEDLINE Enzyme Link: MEDLINE 1.1.1.196

EC number:1.1.1.196

MSA:

1.1.1.196;
Phylogenetic Tree:

1.1.1.196;
Uniprot:
M-CSA:
RHEA:20744 NADP(+) + prostaglandin D2 = 15-dehydro-prostaglandin D2 + H(+) + NADPH
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1
Reaction
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References

TitleAuthorsDatePubMed ID
An NADP-linked prostaglandin D dehydrogenase in swine brain.Watanabe K, Shimizu T, Iguchi S, Wakatsuka H, Hayashi M, Hayaishi O1980 Mar 107354056