EC number:1.1.1.203
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.203 |
|---|---|
| Description: | Uronate dehydrogenase. |
| Alternative Name: |
Uronic acid dehydrogenase. |
| Cath: | 3.40.50.720; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.203 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.203 |
| KEGG Enzyme Link: | KEGG1.1.1.203 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.203 |
| ExPASy Enzyme Link: | ExPASy1.1.1.203 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.203 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.203 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.203 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.203 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.203 |
EC number:1.1.1.203
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:43500 | beta-D-glucuronate + NAD(+) = D-glucaro-1,5-lactone + H(+) + NADH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Characterization of a novel Agrobacterium tumefaciens galactarolactone cycloisomerase enzyme for direct conversion of D-galactarolactone to 3-deoxy-2-keto-L-threo-hexarate. | Andberg M, Maaheimo H, Boer H, Penttilä M, Koivula A, Richard P | 2012 May 18 | 22493433 |
| Crystal structure of uronate dehydrogenase from Agrobacterium tumefaciens. | Parkkinen T, Boer H, Jänis J, Andberg M, Penttilä M, Koivula A, Rouvinen J | 2011 Aug 5 | 21676870 |
| Identification in Agrobacterium tumefaciens of the D-galacturonic acid dehydrogenase gene. | Boer H, Maaheimo H, Koivula A, Penttilä M, Richard P | 2010 Apr | 19921179 |
| Cloning and characterization of uronate dehydrogenases from two pseudomonads and Agrobacterium tumefaciens strain C58. | Yoon SH, Moon TS, Iranpour P, Lanza AM, Prather KJ | 2009 Mar | 19060141 |
| RHEA:22404 | beta-D-galacturonate + NAD(+) = D-galactaro-1,5-lactone + H(+) + NADH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Characterization of a novel Agrobacterium tumefaciens galactarolactone cycloisomerase enzyme for direct conversion of D-galactarolactone to 3-deoxy-2-keto-L-threo-hexarate. | Andberg M, Maaheimo H, Boer H, Penttilä M, Koivula A, Richard P | 2012 May 18 | 22493433 |
| Crystal structure of uronate dehydrogenase from Agrobacterium tumefaciens. | Parkkinen T, Boer H, Jänis J, Andberg M, Penttilä M, Koivula A, Rouvinen J | 2011 Aug 5 | 21676870 |
| Identification in Agrobacterium tumefaciens of the D-galacturonic acid dehydrogenase gene. | Boer H, Maaheimo H, Koivula A, Penttilä M, Richard P | 2010 Apr | 19921179 |
| Cloning and characterization of uronate dehydrogenases from two pseudomonads and Agrobacterium tumefaciens strain C58. | Yoon SH, Moon TS, Iranpour P, Lanza AM, Prather KJ | 2009 Mar | 19060141 |