EC number:1.1.1.261

Enzyme

Download
EC Tree
     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.261
Description:sn-glycerol-1-phosphate dehydrogenase.
Alternative Name: Gro1PDH.
Glycerol-1-phosphate dehydrogenase (NAD(P)(+)).
Cath: 1.20.1090.10; 3.20.20.390; 3.40.50.1970;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.261
BRENDA Enzyme Link: BRENDA 1.1.1.261
KEGG Enzyme Link: KEGG1.1.1.261
BioCyc Enzyme Link: BioCyc 1.1.1.261
ExPASy Enzyme Link: ExPASy1.1.1.261
EC2PDB Enzyme Link: EC2PDB 1.1.1.261
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.261
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.261
IntEnz Enzyme Link: IntEnz 1.1.1.261
MEDLINE Enzyme Link: MEDLINE 1.1.1.261

EC number:1.1.1.261

MSA:

1.1.1.261;
Phylogenetic Tree:

1.1.1.261;
Uniprot:
M-CSA:
RHEA:21416 NADP(+) + sn-glycerol 1-phosphate = dihydroxyacetone phosphate + H(+) + NADPH
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Purification and properties of sn-glycerol-1-phosphate dehydrogenase from Methanobacterium thermoautotrophicum: characterization of the biosynthetic enzyme for the enantiomeric glycerophosphate backbone of ether polar lipids of Archaea.Nishihara M, Koga Y1997 Sep9348086
Reconstruction of the archaeal isoprenoid ether lipid biosynthesis pathway in Escherichia coli through digeranylgeranylglyceryl phosphate.Lai D, Lluncor B, Schröder I, Gunsalus RP, Liao JC, Monbouquette HG2009 May19558961
Identification and characterization of a bacterial glycerol-1-phosphate dehydrogenase: Ni(2+)-dependent AraM from Bacillus subtilis.Guldan H, Sterner R, Babinger P2008 Jul 1518558723
Active site of Zn(2+)-dependent sn-glycerol-1-phosphate dehydrogenase from Aeropyrum pernix K1.Han JS, Ishikawa K2005 May15876564
Kinetic study of sn-glycerol-1-phosphate dehydrogenase from the aerobic hyperthermophilic archaeon, Aeropyrum pernix K1.Han JS, Kosugi Y, Ishida H, Ishikawa K2002 Feb11846799
RHEA:21412 NAD(+) + sn-glycerol 1-phosphate = dihydroxyacetone phosphate + H(+) + NADH
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Purification and properties of sn-glycerol-1-phosphate dehydrogenase from Methanobacterium thermoautotrophicum: characterization of the biosynthetic enzyme for the enantiomeric glycerophosphate backbone of ether polar lipids of Archaea.Nishihara M, Koga Y1997 Sep9348086
Reconstruction of the archaeal isoprenoid ether lipid biosynthesis pathway in Escherichia coli through digeranylgeranylglyceryl phosphate.Lai D, Lluncor B, Schröder I, Gunsalus RP, Liao JC, Monbouquette HG2009 May19558961
Identification and characterization of a bacterial glycerol-1-phosphate dehydrogenase: Ni(2+)-dependent AraM from Bacillus subtilis.Guldan H, Sterner R, Babinger P2008 Jul 1518558723
Active site of Zn(2+)-dependent sn-glycerol-1-phosphate dehydrogenase from Aeropyrum pernix K1.Han JS, Ishikawa K2005 May15876564
Kinetic study of sn-glycerol-1-phosphate dehydrogenase from the aerobic hyperthermophilic archaeon, Aeropyrum pernix K1.Han JS, Kosugi Y, Ishida H, Ishikawa K2002 Feb11846799