EC number:1.1.1.266
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.266 |
|---|---|
| Description: | dTDP-4-dehydro-6-deoxyglucose reductase. |
| Alternative Name: |
dTDP-4-keto-6-deoxyglucose reductase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.266 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.266 |
| KEGG Enzyme Link: | KEGG1.1.1.266 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.266 |
| ExPASy Enzyme Link: | ExPASy1.1.1.266 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.266 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.266 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.266 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.266 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.266 |
EC number:1.1.1.266
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:36583 | dTDP-alpha-D-fucose + NADP(+) = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADPH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Characterization of the dTDP-D-fucofuranose biosynthetic pathway in Escherichia coli O52. | Wang Q, Ding P, Perepelov AV, Xu Y, Wang Y, Knirel YA, Wang L, Feng L | 2008 Dec | 19019146 |
| The dTDP-4-dehydro-6-deoxyglucose reductase encoding fcd gene is part of the surface layer glycoprotein glycosylation gene cluster of Geobacillus tepidamans GS5-97T. | Zayni S, Steiner K, Pföstl A, Hofinger A, Kosma P, Schäffer C, Messner P | 2007 Apr | 17202151 |
| A novel NDP-6-deoxyhexosyl-4-ulose reductase in the pathway for the synthesis of thymidine diphosphate-D-fucose. | Yoshida Y, Nakano Y, Nezu T, Yamashita Y, Koga T | 1999 Jun 11 | 10358040 |
| RHEA:36579 | dTDP-alpha-D-fucose + NAD(+) = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Characterization of the dTDP-D-fucofuranose biosynthetic pathway in Escherichia coli O52. | Wang Q, Ding P, Perepelov AV, Xu Y, Wang Y, Knirel YA, Wang L, Feng L | 2008 Dec | 19019146 |
| The dTDP-4-dehydro-6-deoxyglucose reductase encoding fcd gene is part of the surface layer glycoprotein glycosylation gene cluster of Geobacillus tepidamans GS5-97T. | Zayni S, Steiner K, Pföstl A, Hofinger A, Kosma P, Schäffer C, Messner P | 2007 Apr | 17202151 |
| A novel NDP-6-deoxyhexosyl-4-ulose reductase in the pathway for the synthesis of thymidine diphosphate-D-fucose. | Yoshida Y, Nakano Y, Nezu T, Yamashita Y, Koga T | 1999 Jun 11 | 10358040 |