Enzyme

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EC Tree
     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.279
Description:(R)-3-hydroxyacid-ester dehydrogenase.
Alternative Name: 3-oxo ester (R)-reductase.
Cath: 1.10.110.40; 1.10.287.3140; 1.10.287.3150; 1.20.1050.120; 1.20.5.3540; 1.20.5.3640; 3.20.20.70; 3.30.1120.10; 3.30.1120.100; 3.30.70.2420;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.279
BRENDA Enzyme Link: BRENDA 1.1.1.279
KEGG Enzyme Link: KEGG1.1.1.279
BioCyc Enzyme Link: BioCyc 1.1.1.279
ExPASy Enzyme Link: ExPASy1.1.1.279
EC2PDB Enzyme Link: EC2PDB 1.1.1.279
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.279
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.279
IntEnz Enzyme Link: IntEnz 1.1.1.279
MEDLINE Enzyme Link: MEDLINE 1.1.1.279
MSA:

1.1.1.279;

Phylogenetic Tree:

1.1.1.279;

Uniprot:
M-CSA:
RHEA:24352 ethyl (R)-3-hydroxyhexanoate + NADP(+) = ethyl 3-oxohexanoate + H(+) + NADPH
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1
Reaction
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References

TitleAuthorsDatePubMed ID
Purification and characterization of two oxidoreductases involved in the enantioselective reduction of 3-oxo, 4-oxo and 5-oxo esters in baker's yeast.Heidlas J, Engel KH, Tressl R1988 Mar 153280313