EC number:1.1.1.302
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.302 |
|---|---|
| Description: | 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase. |
| Alternative Name: |
2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase. |
| Cath: | 3.40.430.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.302 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.302 |
| KEGG Enzyme Link: | KEGG1.1.1.302 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.302 |
| ExPASy Enzyme Link: | ExPASy1.1.1.302 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.302 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.302 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.302 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.302 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.302 |
EC number:1.1.1.302
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:27278 | 2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NADP(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + H(+) + NADPH |
| RULE(radius=1) | ([*:1]-[CH2;+0:2]-[*:3].[*:4]-[OH;+0:5]).[*:6]-[n+;H0:7]1:[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:[c;H0;+0:11](-[*:12]):[cH;+0:13]:1>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:5]-[*:4].[*:6]-[N;H0;+0:7]1-[CH;+0:8]=[CH;+0:9]-[CH2;+0:10]-[C;H0;+0:11](-[*:12])=[CH;+0:13]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate synthases of fungi and archaea. | Römisch-Margl W, Eisenreich W, Haase I, Bacher A, Fischer M | 2008 Sep | 18671734 |
| Biosynthesis of riboflavin: structure and properties of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase of Methanocaldococcus jannaschii. | Chatwell L, Krojer T, Fidler A, Römisch W, Eisenreich W, Bacher A, Huber R, Fischer M | 2006 Jun 23 | 16730025 |
| The pyrimidine nucleotide reductase step in riboflavin and F(420) biosynthesis in archaea proceeds by the eukaryotic route to riboflavin. | Graupner M, Xu H, White RH | 2002 Apr | 11889103 |
| RHEA:27274 | 2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NAD(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + H(+) + NADH |
| RULE(radius=1) | ([*:1]-[CH2;+0:2]-[*:3].[*:4]-[OH;+0:5]).[*:6]-[n+;H0:7]1:[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:[c;H0;+0:11](-[*:12]):[cH;+0:13]:1>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:5]-[*:4].[*:6]-[N;H0;+0:7]1-[CH;+0:8]=[CH;+0:9]-[CH2;+0:10]-[C;H0;+0:11](-[*:12])=[CH;+0:13]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate synthases of fungi and archaea. | Römisch-Margl W, Eisenreich W, Haase I, Bacher A, Fischer M | 2008 Sep | 18671734 |
| Biosynthesis of riboflavin: structure and properties of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase of Methanocaldococcus jannaschii. | Chatwell L, Krojer T, Fidler A, Römisch W, Eisenreich W, Bacher A, Huber R, Fischer M | 2006 Jun 23 | 16730025 |
| The pyrimidine nucleotide reductase step in riboflavin and F(420) biosynthesis in archaea proceeds by the eukaryotic route to riboflavin. | Graupner M, Xu H, White RH | 2002 Apr | 11889103 |