EC number:1.1.1.306
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.306 | ||
|---|---|---|---|
| Description: | S-(hydroxymethyl)mycothiol dehydrogenase. | ||
| Alternative Name: |
NAD/factor-dependent formaldehyde dehydrogenase. Mycothiol-dependent formaldehyde dehydrogenase. | ||
| Prosite: | PDOC00058; | ||
| PDB: |
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3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.306 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.306 |
| KEGG Enzyme Link: | KEGG1.1.1.306 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.306 |
| ExPASy Enzyme Link: | ExPASy1.1.1.306 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.306 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.306 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.306 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.306 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.306 |
EC number:1.1.1.306
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:28502 | NAD(+) + S-(hydroxymethyl)mycothiol = H(+) + NADH + S-formylmycothiol |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[OH;+0:3].[*:4]-[n+;H0:5]1:[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:[c;H0;+0:9](-[*:10]):[cH;+0:11]:1>>[*:1]-[CH;+0:2]=[O;H0;+0:3].[*:4]-[N;H0;+0:5]1-[CH;+0:6]=[CH;+0:7]-[CH2;+0:8]-[C;H0;+0:9](-[*:10])=[CH;+0:11]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Mycothiol-dependent formaldehyde dehydrogenase, a prokaryotic medium-chain dehydrogenase/reductase, phylogenetically links different eukaroytic alcohol dehydrogenases--primary structure, conformational modelling and functional correlations. | Norin A, Van Ophem PW, Piersma SR, Persson B, Duine JA, Jörnvall H | 1997 Sep 1 | 9346279 |
| Mycothiol, 1-O-(2'-[N-acetyl-L-cysteinyl]amido-2'-deoxy-alpha-D-glucopyranosyl)-D- myo-inositol, is the factor of NAD/factor-dependent formaldehyde dehydrogenase. | Misset-Smits M, van Ophem PW, Sakuda S, Duine JA | 1997 Jun 9 | 9202149 |
| Mycothiol-dependent proteins in actinomycetes. | Rawat M, Av-Gay Y | 2007 Apr | 17286835 |