Enzyme

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     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.307
Description:D-xylose reductase.
Cath: 3.20.20.10; 3.20.20.100;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.307
BRENDA Enzyme Link: BRENDA 1.1.1.307
KEGG Enzyme Link: KEGG1.1.1.307
BioCyc Enzyme Link: BioCyc 1.1.1.307
ExPASy Enzyme Link: ExPASy1.1.1.307
EC2PDB Enzyme Link: EC2PDB 1.1.1.307
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.307
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.307
IntEnz Enzyme Link: IntEnz 1.1.1.307
MEDLINE Enzyme Link: MEDLINE 1.1.1.307
MSA:

1.1.1.307;

Phylogenetic Tree:

1.1.1.307;

Uniprot:
M-CSA:
RHEA:27445 NADP(+) + xylitol = D-xylose + H(+) + NADPH
RULE(radius=1) ([*:1]-[CH2;+0:2]-[*:3].[*:4]-[OH;+0:5]).[*:6]-[n+;H0:7]1:[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:[c;H0;+0:11](-[*:12]):[cH;+0:13]:1>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:5]-[*:4].[*:6]-[N;H0;+0:7]1-[CH;+0:8]=[CH;+0:9]-[CH2;+0:10]-[C;H0;+0:11](-[*:12])=[CH;+0:13]-1
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
NAD(P)H-dependent aldose reductase from the xylose-assimilating yeast Candida tenuis. Isolation, characterization and biochemical properties of the enzyme.Neuhauser W, Haltrich D, Kulbe KD, Nidetzky B1997 Sep 159307017
Purification, crystallization and preliminary X-ray crystallographic analysis of xylose reductase from Candida tropicalis.Chen LC, Huang SC, Chuankhayan P, Chen CD, Huang YC, Jeyakanthan J, Pang HF, Men LC, Chen YC, Wang YK, Liu MY, Wu TK, Chen CJ2009 Apr 119342796

RHEA:27441 NAD(+) + xylitol = D-xylose + H(+) + NADH
RULE(radius=1) ([*:1]-[CH2;+0:2]-[*:3].[*:4]-[OH;+0:5]).[*:6]-[n+;H0:7]1:[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:[c;H0;+0:11](-[*:12]):[cH;+0:13]:1>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:5]-[*:4].[*:6]-[N;H0;+0:7]1-[CH;+0:8]=[CH;+0:9]-[CH2;+0:10]-[C;H0;+0:11](-[*:12])=[CH;+0:13]-1
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
NAD(P)H-dependent aldose reductase from the xylose-assimilating yeast Candida tenuis. Isolation, characterization and biochemical properties of the enzyme.Neuhauser W, Haltrich D, Kulbe KD, Nidetzky B1997 Sep 159307017
Purification, crystallization and preliminary X-ray crystallographic analysis of xylose reductase from Candida tropicalis.Chen LC, Huang SC, Chuankhayan P, Chen CD, Huang YC, Jeyakanthan J, Pang HF, Men LC, Chen YC, Wang YK, Liu MY, Wu TK, Chen CJ2009 Apr 119342796