EC number:1.1.1.312

Enzyme

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     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.312
Description:2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase.
Alternative Name: 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.312
BRENDA Enzyme Link: BRENDA 1.1.1.312
KEGG Enzyme Link: KEGG1.1.1.312
BioCyc Enzyme Link: BioCyc 1.1.1.312
ExPASy Enzyme Link: ExPASy1.1.1.312
EC2PDB Enzyme Link: EC2PDB 1.1.1.312
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.312
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.312
IntEnz Enzyme Link: IntEnz 1.1.1.312
MEDLINE Enzyme Link: MEDLINE 1.1.1.312

EC number:1.1.1.312

MSA:

1.1.1.312;
Phylogenetic Tree:

1.1.1.312;
Uniprot:
M-CSA:
RHEA:29587 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal + NADP(+) = 2-oxo-2H-pyran-4,6-dicarboxylate + H(+) + NADPH
RULE(radius=1) [*:1]-[C;H0;+0:2]1=[CH;+0:3]-[C;H0;+0:4](-[*:5])=[CH;+0:6]-[CH;+0:7](-[OH;+0:8])-[O;H0;+0:9]-1.[*:10]-[n+;H0:11]1:[cH;+0:12]:[cH;+0:13]:[cH;+0:14]:[c;H0;+0:15](-[*:16]):[cH;+0:17]:1>>[*:10]-[N;H0;+0:11]1-[CH;+0:12]=[CH;+0:13]-[CH2;+0:14]-[C;H0;+0:15](-[*:16])=[CH;+0:17]-1.[*:1]-[c;H0;+0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[c;H0;+0:7](=[O;H0;+0:8]):[o;H0;+0:9]:1
Reaction
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References

TitleAuthorsDatePubMed ID
Purification and properties of 2-pyrone-4,6-dicarboxylate hydrolase.Maruyama K1983 Feb6841353
Isolation and identification of the reaction product of alpha-hydroxy-gamma-carboxymuconic epsilon-semialdehyde dehydrogenase.Maruyama K1979 Dec528534
Interaction of 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase with Reactive Blue 2 and related dyes.Maruyama K1988 Apr3170510
Purification and properties of alpha-hydroxy-gamma-carboxymuconic epsilon-semialdehyde dehydrogenase.Maruyama K, Ariga N, Tsuda M, Deguchi K1978 Apr26671
Genetic and biochemical characterization of 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase and its role in the protocatechuate 4,5-cleavage pathway in Sphingomonas paucimobilis SYK-6.Masai E, Momose K, Hara H, Nishikawa S, Katayama Y, Fukuda M2000 Dec11073908