EC Tree |
1. Oxidoreductases |
1.1 Acting on the CH-OH group of donors |
1.1.1 With NAD+ or NADP+ as acceptor |
ID: | 1.1.1.318 |
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Description: | Eugenol synthase. |
Alternative Name: |
EGS2. |
Cath: | 3.40.50.720; 3.90.25.10; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 1.1.1.318 |
BRENDA Enzyme Link: | BRENDA 1.1.1.318 |
KEGG Enzyme Link: | KEGG1.1.1.318 |
BioCyc Enzyme Link: | BioCyc 1.1.1.318 |
ExPASy Enzyme Link: | ExPASy1.1.1.318 |
EC2PDB Enzyme Link: | EC2PDB 1.1.1.318 |
ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.318 |
PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.318 |
IntEnz Enzyme Link: | IntEnz 1.1.1.318 |
MEDLINE Enzyme Link: | MEDLINE 1.1.1.318 |
MSA: | |
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Phylogenetic Tree: | |
Uniprot: | |
M-CSA: |
RHEA:32655 | a carboxylate + eugenol + NADP(+) = a coniferyl ester + NADPH |
RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH;+0:3]=[CH2;+0:4].[*:5]-[OH;+0:6].[*:7]-[n+;H0:8]1:[cH;+0:9]:[cH;+0:10]:[cH;+0:11]:[c;H0;+0:12](-[*:13]):[cH;+0:14]:1>>[*:1]-[CH;+0:2]=[CH;+0:3]-[CH2;+0:4]-[O;H0;+0:6]-[*:5].[*:7]-[N;H0;+0:8]1-[CH;+0:9]=[CH;+0:10]-[CH2;+0:11]-[C;H0;+0:12](-[*:13])=[CH;+0:14]-1 |
Reaction | ![]() |
Core-to-Core |
Title | Authors | Date | PubMed ID |
---|---|---|---|
Biosynthesis of t-anethole in anise: characterization of t-anol/isoeugenol synthase and an O-methyltransferase specific for a C7-C8 propenyl side chain. | Koeduka T, Baiga TJ, Noel JP, Pichersky E | 2009 Jan | 18987218 |
The multiple phenylpropene synthases in both Clarkia breweri and Petunia hybrida represent two distinct protein lineages. | Koeduka T, Louie GV, Orlova I, Kish CM, Ibdah M, Wilkerson CG, Bowman ME, Baiga TJ, Noel JP, Dudareva N, Pichersky E | 2008 May | 18208524 |
Structure and reaction mechanism of basil eugenol synthase. | Louie GV, Baiga TJ, Bowman ME, Koeduka T, Taylor JH, Spassova SM, Pichersky E, Noel JP | 2007 Oct 3 | 17912370 |
A pinoresinol-lariciresinol reductase homologue from the creosote bush (Larrea tridentata) catalyzes the efficient in vitro conversion of p-coumaryl/coniferyl alcohol esters into the allylphenols chavicol/eugenol, but not the propenylphenols p-anol/isoeugenol. | Vassão DG, Kim SJ, Milhollan JK, Eichinger D, Davin LB, Lewis NG | 2007 Sep 1 | 17624297 |
Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester. | Koeduka T, Fridman E, Gang DR, Vassão DG, Jackson BL, Kish CM, Orlova I, Spassova SM, Lewis NG, Noel JP, Baiga TJ, Dudareva N, Pichersky E | 2006 Jun 27 | 16782809 |
RHEA:24690 | acetate + eugenol + NADP(+) = coniferyl acetate + NADPH |
RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH;+0:3]=[CH2;+0:4].[*:5]-[OH;+0:6].[*:7]-[n+;H0:8]1:[cH;+0:9]:[cH;+0:10]:[cH;+0:11]:[c;H0;+0:12](-[*:13]):[cH;+0:14]:1>>[*:1]-[CH;+0:2]=[CH;+0:3]-[CH2;+0:4]-[O;H0;+0:6]-[*:5].[*:7]-[N;H0;+0:8]1-[CH;+0:9]=[CH;+0:10]-[CH2;+0:11]-[C;H0;+0:12](-[*:13])=[CH;+0:14]-1 |
Reaction | ![]() |
Core-to-Core |
Title | Authors | Date | PubMed ID |
---|---|---|---|
Biosynthesis of t-anethole in anise: characterization of t-anol/isoeugenol synthase and an O-methyltransferase specific for a C7-C8 propenyl side chain. | Koeduka T, Baiga TJ, Noel JP, Pichersky E | 2009 Jan | 18987218 |
The multiple phenylpropene synthases in both Clarkia breweri and Petunia hybrida represent two distinct protein lineages. | Koeduka T, Louie GV, Orlova I, Kish CM, Ibdah M, Wilkerson CG, Bowman ME, Baiga TJ, Noel JP, Dudareva N, Pichersky E | 2008 May | 18208524 |
Structure and reaction mechanism of basil eugenol synthase. | Louie GV, Baiga TJ, Bowman ME, Koeduka T, Taylor JH, Spassova SM, Pichersky E, Noel JP | 2007 Oct 3 | 17912370 |
A pinoresinol-lariciresinol reductase homologue from the creosote bush (Larrea tridentata) catalyzes the efficient in vitro conversion of p-coumaryl/coniferyl alcohol esters into the allylphenols chavicol/eugenol, but not the propenylphenols p-anol/isoeugenol. | Vassão DG, Kim SJ, Milhollan JK, Eichinger D, Davin LB, Lewis NG | 2007 Sep 1 | 17624297 |
Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester. | Koeduka T, Fridman E, Gang DR, Vassão DG, Jackson BL, Kish CM, Orlova I, Spassova SM, Lewis NG, Noel JP, Baiga TJ, Dudareva N, Pichersky E | 2006 Jun 27 | 16782809 |