Enzyme

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     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.318
Description:Eugenol synthase.
Alternative Name: EGS2.
Cath: 3.40.50.720; 3.90.25.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.318
BRENDA Enzyme Link: BRENDA 1.1.1.318
KEGG Enzyme Link: KEGG1.1.1.318
BioCyc Enzyme Link: BioCyc 1.1.1.318
ExPASy Enzyme Link: ExPASy1.1.1.318
EC2PDB Enzyme Link: EC2PDB 1.1.1.318
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.318
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.318
IntEnz Enzyme Link: IntEnz 1.1.1.318
MEDLINE Enzyme Link: MEDLINE 1.1.1.318
MSA:

1.1.1.318;

Phylogenetic Tree:

1.1.1.318;

Uniprot:
M-CSA:
RHEA:32655 a carboxylate + eugenol + NADP(+) = a coniferyl ester + NADPH
RULE(radius=1) [*:1]-[CH2;+0:2]-[CH;+0:3]=[CH2;+0:4].[*:5]-[OH;+0:6].[*:7]-[n+;H0:8]1:[cH;+0:9]:[cH;+0:10]:[cH;+0:11]:[c;H0;+0:12](-[*:13]):[cH;+0:14]:1>>[*:1]-[CH;+0:2]=[CH;+0:3]-[CH2;+0:4]-[O;H0;+0:6]-[*:5].[*:7]-[N;H0;+0:8]1-[CH;+0:9]=[CH;+0:10]-[CH2;+0:11]-[C;H0;+0:12](-[*:13])=[CH;+0:14]-1
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Biosynthesis of t-anethole in anise: characterization of t-anol/isoeugenol synthase and an O-methyltransferase specific for a C7-C8 propenyl side chain.Koeduka T, Baiga TJ, Noel JP, Pichersky E2009 Jan18987218
The multiple phenylpropene synthases in both Clarkia breweri and Petunia hybrida represent two distinct protein lineages.Koeduka T, Louie GV, Orlova I, Kish CM, Ibdah M, Wilkerson CG, Bowman ME, Baiga TJ, Noel JP, Dudareva N, Pichersky E2008 May18208524
Structure and reaction mechanism of basil eugenol synthase.Louie GV, Baiga TJ, Bowman ME, Koeduka T, Taylor JH, Spassova SM, Pichersky E, Noel JP2007 Oct 317912370
A pinoresinol-lariciresinol reductase homologue from the creosote bush (Larrea tridentata) catalyzes the efficient in vitro conversion of p-coumaryl/coniferyl alcohol esters into the allylphenols chavicol/eugenol, but not the propenylphenols p-anol/isoeugenol.Vassão DG, Kim SJ, Milhollan JK, Eichinger D, Davin LB, Lewis NG2007 Sep 117624297
Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester.Koeduka T, Fridman E, Gang DR, Vassão DG, Jackson BL, Kish CM, Orlova I, Spassova SM, Lewis NG, Noel JP, Baiga TJ, Dudareva N, Pichersky E2006 Jun 2716782809

RHEA:24690 acetate + eugenol + NADP(+) = coniferyl acetate + NADPH
RULE(radius=1) [*:1]-[CH2;+0:2]-[CH;+0:3]=[CH2;+0:4].[*:5]-[OH;+0:6].[*:7]-[n+;H0:8]1:[cH;+0:9]:[cH;+0:10]:[cH;+0:11]:[c;H0;+0:12](-[*:13]):[cH;+0:14]:1>>[*:1]-[CH;+0:2]=[CH;+0:3]-[CH2;+0:4]-[O;H0;+0:6]-[*:5].[*:7]-[N;H0;+0:8]1-[CH;+0:9]=[CH;+0:10]-[CH2;+0:11]-[C;H0;+0:12](-[*:13])=[CH;+0:14]-1
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Biosynthesis of t-anethole in anise: characterization of t-anol/isoeugenol synthase and an O-methyltransferase specific for a C7-C8 propenyl side chain.Koeduka T, Baiga TJ, Noel JP, Pichersky E2009 Jan18987218
The multiple phenylpropene synthases in both Clarkia breweri and Petunia hybrida represent two distinct protein lineages.Koeduka T, Louie GV, Orlova I, Kish CM, Ibdah M, Wilkerson CG, Bowman ME, Baiga TJ, Noel JP, Dudareva N, Pichersky E2008 May18208524
Structure and reaction mechanism of basil eugenol synthase.Louie GV, Baiga TJ, Bowman ME, Koeduka T, Taylor JH, Spassova SM, Pichersky E, Noel JP2007 Oct 317912370
A pinoresinol-lariciresinol reductase homologue from the creosote bush (Larrea tridentata) catalyzes the efficient in vitro conversion of p-coumaryl/coniferyl alcohol esters into the allylphenols chavicol/eugenol, but not the propenylphenols p-anol/isoeugenol.Vassão DG, Kim SJ, Milhollan JK, Eichinger D, Davin LB, Lewis NG2007 Sep 117624297
Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester.Koeduka T, Fridman E, Gang DR, Vassão DG, Jackson BL, Kish CM, Orlova I, Spassova SM, Lewis NG, Noel JP, Baiga TJ, Dudareva N, Pichersky E2006 Jun 2716782809