| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.319 |
|---|---|
| Description: | Isoeugenol synthase. |
| Alternative Name: |
T-anol/isoeugenol synthase 1. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.1.1.319 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.319 |
| KEGG Enzyme Link: | KEGG1.1.1.319 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.319 |
| ExPASy Enzyme Link: | ExPASy1.1.1.319 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.319 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.319 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.319 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.319 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.319 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:36243 | acetate + NADP(+) + trans-anol = NADPH + trans-coumaryl acetate |
| RULE(radius=1) | [*:1]-[CH3;+0:2].[*:3]-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[CH2;+0:2]-[O;H0;+0:4]-[*:3].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Biosynthesis of t-anethole in anise: characterization of t-anol/isoeugenol synthase and an O-methyltransferase specific for a C7-C8 propenyl side chain. | Koeduka T, Baiga TJ, Noel JP, Pichersky E | 2009 Jan | 18987218 |
| RHEA:24694 | acetate + NADP(+) + trans-isoeugenol = coniferyl acetate + NADPH |
| RULE(radius=1) | [*:1]-[CH3;+0:2].[*:3]-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[CH2;+0:2]-[O;H0;+0:4]-[*:3].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Biosynthesis of t-anethole in anise: characterization of t-anol/isoeugenol synthase and an O-methyltransferase specific for a C7-C8 propenyl side chain. | Koeduka T, Baiga TJ, Noel JP, Pichersky E | 2009 Jan | 18987218 |
| The multiple phenylpropene synthases in both Clarkia breweri and Petunia hybrida represent two distinct protein lineages. | Koeduka T, Louie GV, Orlova I, Kish CM, Ibdah M, Wilkerson CG, Bowman ME, Baiga TJ, Noel JP, Dudareva N, Pichersky E | 2008 May | 18208524 |
| Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester. | Koeduka T, Fridman E, Gang DR, Vassão DG, Jackson BL, Kish CM, Orlova I, Spassova SM, Lewis NG, Noel JP, Baiga TJ, Dudareva N, Pichersky E | 2006 Jun 27 | 16782809 |