EC number:1.1.1.328
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.328 |
|---|---|
| Description: | Nicotine blue oxidoreductase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.328 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.328 |
| KEGG Enzyme Link: | KEGG1.1.1.328 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.328 |
| ExPASy Enzyme Link: | ExPASy1.1.1.328 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.328 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.328 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.328 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.328 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.328 |
EC number:1.1.1.328
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:34027 | 3,3'-bipyridine-2,2',5,5',6,6'-hexol + NADP(+) = (E)-2,2',5,5'-tetrahydroxy-6H,6'H-(3,3'-bipyridinylidene)-6,6'-dione + 3 H(+) + NADPH |
| RULE(radius=1) | [*:1]-[c;H0;+0:2]1:[n;H0;+0:3]:[c;H0;+0:4](-[OH;+0:5]):[c;H0;+0:6](-[*:7]):[cH;+0:8]:[c;H0;+0:9]:1-[c;H0;+0:10]1:[cH;+0:11]:[c;H0;+0:12](-[*:13]):[c;H0;+0:14](-[OH;+0:15]):[n;H0;+0:16]:[c;H0;+0:17]:1-[*:18].[*:19]-[n+;H0:20]1:[cH;+0:21]:[cH;+0:22]:[cH;+0:23]:[c;H0;+0:24](-[*:25]):[cH;+0:26]:1>>[*:1]-[C;H0;+0:2]1=[N;H0;+0:3]-[C;H0;+0:4](=[O;H0;+0:5])-[C;H0;+0:6](-[*:7])=[CH;+0:8]-[C;H0;+0:9]-1=[C;H0;+0:10]1-[CH;+0:11]=[C;H0;+0:12](-[*:13])-[C;H0;+0:14](=[O;H0;+0:15])-[N;H0;+0:16]=[C;H0;+0:17]-1-[*:18].[*:19]-[N;H0;+0:20]1-[CH;+0:21]=[CH;+0:22]-[CH2;+0:23]-[C;H0;+0:24](-[*:25])=[CH;+0:26]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| An NAD(P)H-nicotine blue oxidoreductase is part of the nicotine regulon and may protect Arthrobacter nicotinovorans from oxidative stress during nicotine catabolism. | Mihasan M, Chiribau CB, Friedrich T, Artenie V, Brandsch R | 2007 Apr | 17293530 |
| RHEA:34023 | 3,3'-bipyridine-2,2',5,5',6,6'-hexol + NAD(+) = (E)-2,2',5,5'-tetrahydroxy-6H,6'H-(3,3'-bipyridinylidene)-6,6'-dione + 3 H(+) + NADH |
| RULE(radius=1) | [*:1]-[c;H0;+0:2]1:[n;H0;+0:3]:[c;H0;+0:4](-[OH;+0:5]):[c;H0;+0:6](-[*:7]):[cH;+0:8]:[c;H0;+0:9]:1-[c;H0;+0:10]1:[cH;+0:11]:[c;H0;+0:12](-[*:13]):[c;H0;+0:14](-[OH;+0:15]):[n;H0;+0:16]:[c;H0;+0:17]:1-[*:18].[*:19]-[n+;H0:20]1:[cH;+0:21]:[cH;+0:22]:[cH;+0:23]:[c;H0;+0:24](-[*:25]):[cH;+0:26]:1>>[*:1]-[C;H0;+0:2]1=[N;H0;+0:3]-[C;H0;+0:4](=[O;H0;+0:5])-[C;H0;+0:6](-[*:7])=[CH;+0:8]-[C;H0;+0:9]-1=[C;H0;+0:10]1-[CH;+0:11]=[C;H0;+0:12](-[*:13])-[C;H0;+0:14](=[O;H0;+0:15])-[N;H0;+0:16]=[C;H0;+0:17]-1-[*:18].[*:19]-[N;H0;+0:20]1-[CH;+0:21]=[CH;+0:22]-[CH2;+0:23]-[C;H0;+0:24](-[*:25])=[CH;+0:26]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| An NAD(P)H-nicotine blue oxidoreductase is part of the nicotine regulon and may protect Arthrobacter nicotinovorans from oxidative stress during nicotine catabolism. | Mihasan M, Chiribau CB, Friedrich T, Artenie V, Brandsch R | 2007 Apr | 17293530 |