EC number:1.1.1.332
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.332 |
|---|---|
| Description: | Chanoclavine-I dehydrogenase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.332 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.332 |
| KEGG Enzyme Link: | KEGG1.1.1.332 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.332 |
| ExPASy Enzyme Link: | ExPASy1.1.1.332 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.332 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.332 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.332 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.332 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.332 |
EC number:1.1.1.332
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:33891 | chanoclavine-I + NAD(+) = chanoclavine-I aldehyde + H(+) + NADH |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[OH;+0:3].[*:4]-[n+;H0:5]1:[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:[c;H0;+0:9](-[*:10]):[cH;+0:11]:1>>[*:1]-[CH;+0:2]=[O;H0;+0:3].[*:4]-[N;H0;+0:5]1-[CH;+0:6]=[CH;+0:7]-[CH2;+0:8]-[C;H0;+0:9](-[*:10])=[CH;+0:11]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Genome mining reveals the presence of a conserved gene cluster for the biosynthesis of ergot alkaloid precursors in the fungal family Arthrodermataceae. | Wallwey C, Heddergott C, Xie X, Brakhage AA, Li SM | 2012 Jun | 22403186 |
| Ergot alkaloid biosynthesis in Aspergillus fumigatus: conversion of chanoclavine-I to chanoclavine-I aldehyde catalyzed by a short-chain alcohol dehydrogenase FgaDH. | Wallwey C, Matuschek M, Li SM | 2010 Feb | 20039019 |