EC number:1.1.1.333
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.333 |
|---|---|
| Description: | Decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose 2-reductase. |
| Alternative Name: |
Decaprenylphospho-beta-D-ribofuranose 2'-epimerase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.333 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.333 |
| KEGG Enzyme Link: | KEGG1.1.1.333 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.333 |
| ExPASy Enzyme Link: | ExPASy1.1.1.333 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.333 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.333 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.333 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.333 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.333 |
EC number:1.1.1.333
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:33895 | NAD(+) + trans,octa-cis-decaprenylphospho-beta-D-arabinofuranose = H(+) + NADH + trans,octa-cis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[c;H0;+0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[n+;H0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[C;H0;+0:6]1=[CH;+0:12]-[N;H0;+0:10](-[*:11])-[CH;+0:9]=[CH;+0:8]-[CH2;+0:7]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-β-D-ribofuranose 2'-oxidase DprE1. | Trefzer C, Škovierová H, Buroni S, Bobovská A, Nenci S, Molteni E, Pojer F, Pasca MR, Makarov V, Cole ST, Riccardi G, Mikušová K, Johnsson K | 2012 Jan 18 | 22188377 |
| Decaprenylphosphoryl arabinofuranose, the donor of the D-arabinofuranosyl residues of mycobacterial arabinan, is formed via a two-step epimerization of decaprenylphosphoryl ribose. | Mikusová K, Huang H, Yagi T, Holsters M, Vereecke D, D'Haeze W, Scherman MS, Brennan PJ, McNeil MR, Crick DC | 2005 Dec | 16291675 |