EC number:1.1.1.335
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.335 |
|---|---|
| Description: | UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase. |
| Cath: | 3.30.360.10; 3.40.50.720; 3.40.640.10; 3.90.1150.10; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.335 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.335 |
| KEGG Enzyme Link: | KEGG1.1.1.335 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.335 |
| ExPASy Enzyme Link: | ExPASy1.1.1.335 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.335 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.335 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.335 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.335 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.335 |
EC number:1.1.1.335
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:33579 | NAD(+) + UDP-N-2-acetamido-2-deoxy-alpha-D-glucuronate = H(+) + NADH + UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Biochemical and structural characterization of WlbA from Bordetella pertussis and Chromobacterium violaceum: enzymes required for the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid. | Thoden JB, Holden HM | 2011 Mar 8 | 21241053 |
| Structural and functional studies of WlbA: A dehydrogenase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid . | Thoden JB, Holden HM | 2010 Sep 14 | 20690587 |
| Biosynthesis of UDP-GlcNAc(3NAc)A by WbpB, WbpE, and WbpD: enzymes in the Wbp pathway responsible for O-antigen assembly in Pseudomonas aeruginosa PAO1. | Larkin A, Imperiali B | 2009 Jun 16 | 19348502 |
| Characterization of WbpB, WbpE, and WbpD and reconstitution of a pathway for the biosynthesis of UDP-2,3-diacetamido-2,3-dideoxy-D-mannuronic acid in Pseudomonas aeruginosa. | Westman EL, McNally DJ, Charchoglyan A, Brewer D, Field RA, Lam JS | 2009 May 1 | 19282284 |