Enzyme

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EC Tree
     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.349
Description:Norsolorinic acid ketoreductase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.349
BRENDA Enzyme Link: BRENDA 1.1.1.349
KEGG Enzyme Link: KEGG1.1.1.349
BioCyc Enzyme Link: BioCyc 1.1.1.349
ExPASy Enzyme Link: ExPASy1.1.1.349
EC2PDB Enzyme Link: EC2PDB 1.1.1.349
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.349
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.349
IntEnz Enzyme Link: IntEnz 1.1.1.349
MEDLINE Enzyme Link: MEDLINE 1.1.1.349
MSA:

1.1.1.349;

Phylogenetic Tree:

1.1.1.349;

Uniprot:
M-CSA:
RHEA:35447 (1'S)-averantin + NADP(+) = H(+) + NADPH + norsolorinic acid
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1
Reaction
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References

TitleAuthorsDatePubMed ID
Stereochemistry during aflatoxin biosynthesis: conversion of norsolorinic acid to averufin.Yabe K, Matsuyama Y, Ando Y, Nakajima H, Hamasaki T1993 Aug8368836
Enzymatic function of the nor-1 protein in aflatoxin biosynthesis in Aspergillus parasiticus.Zhou R, Linz JE1999 Dec10584035