EC number:1.1.1.364
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.364 |
|---|---|
| Description: | dTDP-4-dehydro-6-deoxy-alpha-D-gulose 4-ketoreductase. |
| Alternative Name: |
dTDP-4-dehydro-6-deoxygulose reductase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.364 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.364 |
| KEGG Enzyme Link: | KEGG1.1.1.364 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.364 |
| ExPASy Enzyme Link: | ExPASy1.1.1.364 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.364 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.364 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.364 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.364 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.364 |
EC number:1.1.1.364
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:39883 | dTDP-6-deoxy-alpha-D-allose + NADP(+) = dTDP-4-dehydro-6-deoxy-alpha-D-allose + H(+) + NADPH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Structural and functional studies on a 3'-epimerase involved in the biosynthesis of dTDP-6-deoxy-D-allose. | Kubiak RL, Phillips RK, Zmudka MW, Ahn MR, Maka EM, Pyeatt GL, Roggensack SJ, Holden HM | 2012 Nov 20 | 23116432 |
| Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP. | Thuy TT, Liou K, Oh TJ, Kim DH, Nam DH, Yoo JC, Sohng JK | 2007 Feb | 17053005 |
| Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida. | Anzai Y, Saito N, Tanaka M, Kinoshita K, Koyama Y, Kato F | 2003 Jan 21 | 12583909 |
| The mycinose-biosynthetic genes of Streptomyces fradiae, producer of tylosin. | Bate N, Cundliffe E | 1999 Aug | 10510490 |
| RHEA:36679 | dTDP-6-deoxy-alpha-D-allose + NAD(+) = dTDP-4-dehydro-6-deoxy-alpha-D-allose + H(+) + NADH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Structural and functional studies on a 3'-epimerase involved in the biosynthesis of dTDP-6-deoxy-D-allose. | Kubiak RL, Phillips RK, Zmudka MW, Ahn MR, Maka EM, Pyeatt GL, Roggensack SJ, Holden HM | 2012 Nov 20 | 23116432 |
| Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP. | Thuy TT, Liou K, Oh TJ, Kim DH, Nam DH, Yoo JC, Sohng JK | 2007 Feb | 17053005 |
| Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida. | Anzai Y, Saito N, Tanaka M, Kinoshita K, Koyama Y, Kato F | 2003 Jan 21 | 12583909 |
| The mycinose-biosynthetic genes of Streptomyces fradiae, producer of tylosin. | Bate N, Cundliffe E | 1999 Aug | 10510490 |