EC number:1.1.1.365

Enzyme

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EC Tree
     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.365
Description:D-galacturonate reductase.
Alternative Name: GalUR.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.365
BRENDA Enzyme Link: BRENDA 1.1.1.365
KEGG Enzyme Link: KEGG1.1.1.365
BioCyc Enzyme Link: BioCyc 1.1.1.365
ExPASy Enzyme Link: ExPASy1.1.1.365
EC2PDB Enzyme Link: EC2PDB 1.1.1.365
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.365
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.365
IntEnz Enzyme Link: IntEnz 1.1.1.365
MEDLINE Enzyme Link: MEDLINE 1.1.1.365

EC number:1.1.1.365

MSA:

1.1.1.365;
Phylogenetic Tree:

1.1.1.365;
Uniprot:
M-CSA:
RHEA:26345 L-galactonate + NADP(+) = aldehydo-D-galacturonate + H(+) + NADPH
RULE(radius=1) [*:1]-[CH2;+0:2]-[OH;+0:3].[*:4]-[n+;H0:5]1:[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:[c;H0;+0:9](-[*:10]):[cH;+0:11]:1>>[*:1]-[CH;+0:2]=[O;H0;+0:3].[*:4]-[N;H0;+0:5]1-[CH;+0:6]=[CH;+0:7]-[CH2;+0:8]-[C;H0;+0:9](-[*:10])=[CH;+0:11]-1
Reaction
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References

TitleAuthorsDatePubMed ID
An evolutionary conserved d-galacturonic acid metabolic pathway operates across filamentous fungi capable of pectin degradation.Martens-Uzunova ES, Schaap PJ2008 Nov18768163
Identification in the mold Hypocrea jecorina of the first fungal D-galacturonic acid reductase.Kuorelahti S, Kalkkinen N, Penttilä M, Londesborough J, Richard P2005 Aug 2316101307
Biological synthesis of ascorbic acid: the conversion of derivatives of D-galacturonic acid into L-ascorbic acid by plant extracts.ISHERWOOD FA, MAPSON LW1956 Sep13363799
Vitamin C booster.Smirnoff N2003 Feb12560838
Engineering increased vitamin C levels in plants by overexpression of a D-galacturonic acid reductase.Agius F, González-Lamothe R, Caballero JL, Muñoz-Blanco J, Botella MA, Valpuesta V2003 Feb12524550