EC number:1.1.1.369

Enzyme

Download
EC Tree
     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.369
Description:D-chiro-inositol 1-dehydrogenase.
Alternative Name: DCI 1-dehydrogenase.
Cath: 3.30.360.10; 3.40.50.720;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.369
BRENDA Enzyme Link: BRENDA 1.1.1.369
KEGG Enzyme Link: KEGG1.1.1.369
BioCyc Enzyme Link: BioCyc 1.1.1.369
ExPASy Enzyme Link: ExPASy1.1.1.369
EC2PDB Enzyme Link: EC2PDB 1.1.1.369
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.369
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.369
IntEnz Enzyme Link: IntEnz 1.1.1.369
MEDLINE Enzyme Link: MEDLINE 1.1.1.369

EC number:1.1.1.369

MSA:

1.1.1.369;
Phylogenetic Tree:

1.1.1.369;
Uniprot:
M-CSA:
RHEA:25832 1D-chiro-inositol + NAD(+) = H(+) + NADH + scyllo-inosine
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1
Reaction
Core-to-Core More
Core-to-Core More

References

TitleAuthorsDatePubMed ID
myo-Inositol catabolism in Bacillus subtilis.Yoshida K, Yamaguchi M, Morinaga T, Kinehara M, Ikeuchi M, Ashida H, Fujita Y2008 Apr 1818310071
Genetic modification of Bacillus subtilis for production of D-chiro-inositol, an investigational drug candidate for treatment of type 2 diabetes and polycystic ovary syndrome.Yoshida K, Yamaguchi M, Morinaga T, Ikeuchi M, Kinehara M, Ashida H2006 Feb16461681
Purification and properties of Bacillus subtilis inositol dehydrogenase.Ramaley R, Fujita Y, Freese E1979 Aug 25112095