EC number:1.1.1.384
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.384 |
|---|---|
| Description: | dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase. |
| Alternative Name: |
dTDP-4-keto-2,6-dideoxy-D-glucose 3-oxidoreductase. dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose 3-oxidoreductase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.384 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.384 |
| KEGG Enzyme Link: | KEGG1.1.1.384 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.384 |
| ExPASy Enzyme Link: | ExPASy1.1.1.384 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.384 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.384 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.384 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.384 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.384 |
EC number:1.1.1.384
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:44624 | dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + NADP(+) = dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + H(+) + NADPH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Combined structural and functional investigation of a C-3''-ketoreductase involved in the biosynthesis of dTDP-L-digitoxose. | Kubiak RL, Holden HM | 2011 Jul 5 | 21598943 |
| In vitro characterization of the enzymes involved in TDP-D-forosamine biosynthesis in the spinosyn pathway of Saccharopolyspora spinosa. | Hong L, Zhao Z, Melançon CE 3rd, Zhang H, Liu HW | 2008 Apr 9 | 18345667 |
| Biosynthesis of the dideoxysugar component of jadomycin B: genes in the jad cluster of Streptomyces venezuelae ISP5230 for L-digitoxose assembly and transfer to the angucycline aglycone. | Wang L, White RL, Vining LC | 2002 Apr | 11932454 |
| Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus. | Aguirrezabalaga I, Olano C, Allende N, Rodriguez L, Braña AF, Méndez C, Salas JA | 2000 May | 10770761 |