EC number:1.1.1.388
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.388 |
|---|---|
| Description: | Glucose-6-phosphate dehydrogenase (NAD(+)). |
| Alternative Name: |
Glc6PDH. |
| Cath: | 3.30.360.10; 3.40.50.720; 3.40.50.1360; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.388 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.388 |
| KEGG Enzyme Link: | KEGG1.1.1.388 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.388 |
| ExPASy Enzyme Link: | ExPASy1.1.1.388 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.388 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.388 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.388 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.388 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.388 |
EC number:1.1.1.388
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:38215 | D-glucose 6-phosphate + NAD(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| On the mechanism of the reaction catalyzed by glucose 6-phosphate dehydrogenase. | Cosgrove MS, Naylor C, Paludan S, Adams MJ, Levy HR | 1998 Mar 3 | 9485426 |
| Purification and characterization of the NAD-preferring glucose 6-phosphate dehydrogenase from Acetobacter hansenii (Acetobacter xylinum). | Ragunathan S, Levy HR | 1994 May 1 | 8179320 |
| Glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroides. Kinetic studies. | Olive C, Geroch ME, Levy HR | 1971 Apr 10 | 4396688 |
| The oxidative pentose phosphate pathway in the haloarchaeon Haloferax volcanii involves a novel type of glucose-6-phosphate dehydrogenase--The archaeal Zwischenferment. | Pickl A, Schönheit P | 2015 Apr 28 | 25836736 |