EC number:1.1.1.393
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.393 |
|---|---|
| Description: | 3-beta-hydroxycholanate 3-dehydrogenase (NADP(+)). |
| Alternative Name: |
3-beta-hydroxysteroid dehydrogenase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.393 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.393 |
| KEGG Enzyme Link: | KEGG1.1.1.393 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.393 |
| ExPASy Enzyme Link: | ExPASy1.1.1.393 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.393 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.393 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.393 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.393 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.393 |
EC number:1.1.1.393
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:47520 | 3-oxo-5beta-cholan-24-oate + H(+) + NADPH = isolithocholate + NADP(+) |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[C;H0;+0:8](-[*:9])-[CH2;+0:10]-[CH;+0:11]=[CH;+0:12]-1.[H+;H0:13]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[c;H0;+0:8](-[*:9]):[cH;+0:10]:[cH;+0:11]:[cH;+0:12]:1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A biosynthetic pathway for a prominent class of microbiota-derived bile acids. | Devlin AS, Fischbach MA | 2015 Sep | 26192599 |
| 3 beta-Hydroxysteroid dehydrogenase of Ruminococcus sp. from human intestinal bacteria. | Akao T, Akao T, Hattori M, Namba T, Kobashi K | 1986 May | 3458705 |