Enzyme

Download
EC Tree
     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.394
Description:Aurachin B dehydrogenase.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.394
BRENDA Enzyme Link: BRENDA 1.1.1.394
KEGG Enzyme Link: KEGG1.1.1.394
BioCyc Enzyme Link: BioCyc 1.1.1.394
ExPASy Enzyme Link: ExPASy1.1.1.394
EC2PDB Enzyme Link: EC2PDB 1.1.1.394
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.394
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.394
IntEnz Enzyme Link: IntEnz 1.1.1.394
MEDLINE Enzyme Link: MEDLINE 1.1.1.394
MSA:

1.1.1.394;

Phylogenetic Tree:

1.1.1.394;

Uniprot:
M-CSA:
RHEA:48720 aurachin B + H2O + NAD(+) = 4-hydroxy-2-methyl-3-oxo-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADH
RULE(radius=1) [*:1]-[n+;H0:2]1:[*:3]:[*:4]:[c;H0;+0:5](-[*:6]):[c;H0;+0:7](-[OH;+0:8]):[c;H0;+0:9]:1-[*:10].[*:11]-[n+;H0:12]1:[cH;+0:13]:[cH;+0:14]:[cH;+0:15]:[c;H0;+0:16](-[*:17]):[cH;+0:18]:1.[OH2;+0:19]>>[*:1]-[N+;H0:2]1=[C;H0;+0:9](-[*:10])-[C;H0;+0:7](=[O;H0;+0:8])-[C;H0;+0:5](-[*:6])(-[OH;+0:19])-[*:4]:[*:3]-1.[*:11]-[N;H0;+0:12]1-[CH;+0:13]=[CH;+0:14]-[CH2;+0:15]-[C;H0;+0:16](-[*:17])=[CH;+0:18]-1
Reaction
Core-to-Core More
Core-to-Core More

References

TitleAuthorsDatePubMed ID
A semipinacol rearrangement directed by an enzymatic system featuring dual-function FAD-dependent monooxygenase.Katsuyama Y, Harmrolfs K, Pistorius D, Li Y, Müller R2012 Sep 1022907798