Enzyme

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EC Tree
     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.402
Description:D-erythritol 1-phosphate dehydrogenase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.402
BRENDA Enzyme Link: BRENDA 1.1.1.402
KEGG Enzyme Link: KEGG1.1.1.402
BioCyc Enzyme Link: BioCyc 1.1.1.402
ExPASy Enzyme Link: ExPASy1.1.1.402
EC2PDB Enzyme Link: EC2PDB 1.1.1.402
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.402
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.402
IntEnz Enzyme Link: IntEnz 1.1.1.402
MEDLINE Enzyme Link: MEDLINE 1.1.1.402
MSA:

1.1.1.402;

Phylogenetic Tree:

1.1.1.402;

Uniprot:
M-CSA:
RHEA:49620 D-erythritol 1-phosphate + NADP(+) = D-erythrulose 1-phosphate + H(+) + NADPH
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1
Reaction
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References

TitleAuthorsDatePubMed ID
Erythritol feeds the pentose phosphate pathway via three new isomerases leading to D-erythrose-4-phosphate in Brucella.Barbier T, Collard F, Zúñiga-Ripa A, Moriyón I, Godard T, Becker J, Wittmann C, Van Schaftingen E, Letesson JJ2014 Dec 1625453104
Erythritol catabolism by Brucella abortus.Sperry JF, Robertson DC1975 Feb163226
The genes for erythritol catabolism are organized as an inducible operon in Brucella abortus.Sangari FJ, Agüero J, García-Lobo JM2000 Feb10708387