Enzyme

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EC Tree
     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.413
Description:A-factor type gamma-butyrolactone 1'-reductase (1S-forming).

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.413
BRENDA Enzyme Link: BRENDA 1.1.1.413
KEGG Enzyme Link: KEGG1.1.1.413
BioCyc Enzyme Link: BioCyc 1.1.1.413
ExPASy Enzyme Link: ExPASy1.1.1.413
EC2PDB Enzyme Link: EC2PDB 1.1.1.413
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.413
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.413
IntEnz Enzyme Link: IntEnz 1.1.1.413
MEDLINE Enzyme Link: MEDLINE 1.1.1.413
MSA:

1.1.1.413;

Phylogenetic Tree:

1.1.1.413;

Uniprot:
M-CSA:
RHEA:18941 a (3R,4R)-3-[(1S)-1-hydroxyalkyl]-4-(hydroxymethyl)oxolan-2-one + NADP(+) = a (3R,4R)-3-alkanoyl-4-(hydroxymethyl)oxolan-2-one + H(+) + NADPH
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1
Reaction
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References

TitleAuthorsDatePubMed ID
barS1, a gene for biosynthesis of a gamma-butyrolactone autoregulator, a microbial signaling molecule eliciting antibiotic production in Streptomyces species.Shikura N, Yamamura J, Nihira T2002 Sep12193632