EC number:1.1.3.6
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.3 With oxygen as acceptor |
| ID: | 1.1.3.6 | ||
|---|---|---|---|
| Description: | Cholesterol oxidase. | ||
| Alternative Name: |
Cholesterol-O(2) oxidoreductase. | ||
| Prosite: | PDOC00543; | ||
| PDB: |
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| Cath: | 3.30.410.10; 3.50.50.60; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.3.6 |
| BRENDA Enzyme Link: | BRENDA 1.1.3.6 |
| KEGG Enzyme Link: | KEGG1.1.3.6 |
| BioCyc Enzyme Link: | BioCyc 1.1.3.6 |
| ExPASy Enzyme Link: | ExPASy1.1.3.6 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.3.6 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.3.6 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.3.6 |
| IntEnz Enzyme Link: | IntEnz 1.1.3.6 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.3.6 |
| RHEA:32183 | cholesterol + O2 = cholest-5-en-3-one + H2O2 |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[O;H0;+0:5]=[O;H0;+0:6]>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[OH;+0:5]-[OH;+0:6] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Cholesterol oxidase is required for virulence of Mycobacterium tuberculosis. | Brzostek A, Dziadek B, Rumijowska-Galewicz A, Pawelczyk J, Dziadek J | 2007 Oct | 17651430 |
| Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants. | Yue QK, Kass IJ, Sampson NS, Vrielink A | 1999 Apr 6 | 10194345 |
| Cholesterol oxidase with high catalytic activity from Pseudomonas aeruginosa: Screening, molecular genetic analysis, expression and characterization. | Doukyu N, Nihei S | 2015 Jul | 25573142 |
| Cholesterol oxidase: structure and function. | Vrielink A | 2010 | 20213543 |