EC number:1.1.5.3
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.5 With a quinone or similar compound as acceptor |
| ID: | 1.1.5.3 | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Description: | Glycerol-3-phosphate dehydrogenase. | ||||||||||||
| Alternative Name: |
sn-glycerol-3-phosphate dehydrogenase. L-glycerophosphate dehydrogenase. Glycerophosphate dehydrogenase. Glycerol-3-phosphate CoQ reductase. Flavin-linked glycerol-3-phosphate dehydrogenase. FAD-dependent glycerol-3-phosphate dehydrogenase. | ||||||||||||
| Prosite: | PDOC00753; | ||||||||||||
| PDB: |
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| Cath: | 1.10.8.870; 1.20.5.3580; 3.30.9.10; 3.50.50.60; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.5.3 |
| BRENDA Enzyme Link: | BRENDA 1.1.5.3 |
| KEGG Enzyme Link: | KEGG1.1.5.3 |
| BioCyc Enzyme Link: | BioCyc 1.1.5.3 |
| ExPASy Enzyme Link: | ExPASy1.1.5.3 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.5.3 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.5.3 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.5.3 |
| IntEnz Enzyme Link: | IntEnz 1.1.5.3 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.5.3 |
| RHEA:18977 | a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[O;H0;+0:5]=[C;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[C;H0;+0:9](=[O;H0;+0:10])-[CH;+0:11]=[CH;+0:12]-1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[OH;+0:5]-[c;H0;+0:6]1:[cH;+0:7]:[cH;+0:8]:[c;H0;+0:9](-[OH;+0:10]):[cH;+0:11]:[cH;+0:12]:1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Steady-state kinetics of reduction of coenzyme Q analogs by glycerol-3-phosphate dehydrogenase in brown adipose tissue mitochondria. | Rauchová H, Fato R, Drahota Z, Lenaz G | 1997 Aug 1 | 9244403 |
| Identification of a mitochondrial glycerol-3-phosphate dehydrogenase from Arabidopsis thaliana: evidence for a mitochondrial glycerol-3-phosphate shuttle in plants. | Shen W, Wei Y, Dauk M, Zheng Z, Zou J | 2003 Feb 11 | 12586344 |
| Aerobic sn-glycerol-3-phosphate dehydrogenase from Escherichia coli binds to the cytoplasmic membrane through an amphipathic alpha-helix. | Walz AC, Demel RA, de Kruijff B, Mutzel R | 2002 Jul 15 | 11955283 |
| RHEA:28751 | sn-glycerol 3-phosphate + ubiquinone-8 = dihydroxyacetone phosphate + ubiquinol-8 |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[C;H0;+0:3](-[*:4])-[C;H0;+0:5](=[O;H0;+0:6])-[C;H0;+0:7](-[*:8])=[C;H0;+0:9](-[*:10])-[C;H0;+0:11]-1=[O;H0;+0:12].[*:13]-[CH;+0:14](-[*:15])-[OH;+0:16]>>[*:13]-[C;H0;+0:14](-[*:15])=[O;H0;+0:16].[*:1]-[c;H0;+0:2]1:[c;H0;+0:3](-[*:4]):[c;H0;+0:5](-[OH;+0:6]):[c;H0;+0:7](-[*:8]):[c;H0;+0:9](-[*:10]):[c;H0;+0:11]:1-[OH;+0:12] |
| Reaction |  |
| Core-to-Core |
| RHEA:28755 | a ubiquinone + sn-glycerol 3-phosphate = a ubiquinol + dihydroxyacetone phosphate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[C;H0;+0:3](-[*:4])-[C;H0;+0:5](=[O;H0;+0:6])-[C;H0;+0:7](-[*:8])=[C;H0;+0:9](-[*:10])-[C;H0;+0:11]-1=[O;H0;+0:12].[*:13]-[CH;+0:14](-[*:15])-[OH;+0:16]>>[*:13]-[C;H0;+0:14](-[*:15])=[O;H0;+0:16].[*:1]-[c;H0;+0:2]1:[c;H0;+0:3](-[*:4]):[c;H0;+0:5](-[OH;+0:6]):[c;H0;+0:7](-[*:8]):[c;H0;+0:9](-[*:10]):[c;H0;+0:11]:1-[OH;+0:12] |
| Reaction |  |
| Core-to-Core |
| RHEA:29219 | a menaquinone + sn-glycerol 3-phosphate = a menaquinol + dihydroxyacetone phosphate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[C;H0;+0:3](-[*:4])-[C;H0;+0:5](=[O;H0;+0:6])-[*:7](:[cH;+0:8]:[*:9]):[c;H0;+0:10](:[*:11])-[C;H0;+0:12]-1=[O;H0;+0:13].[*:14]-[CH;+0:15](-[*:16])-[OH;+0:17]>>[*:14]-[C;H0;+0:15](-[*:16])=[O;H0;+0:17].[*:1]-[c;H0;+0:2]1:[c;H0;+0:3](-[*:4]):[c;H0;+0:5](-[OH;+0:6]):[*:7](:[cH;+0:10]:[*:11]):[c;H0;+0:8](:[*:9]):[c;H0;+0:12]:1-[OH;+0:13] |
| Reaction |  |
| Core-to-Core |