EC number:1.1.5.4
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.5 With a quinone or similar compound as acceptor |
| ID: | 1.1.5.4 |
|---|---|
| Description: | Malate dehydrogenase (quinone). |
| Alternative Name: |
MQO. Malate quinone oxidoreductase. Malate dehydrogenase (acceptor). FAD-dependent malate dehydrogenase. |
| Cath: | 3.40.50.720; 3.90.110.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.5.4 |
| BRENDA Enzyme Link: | BRENDA 1.1.5.4 |
| KEGG Enzyme Link: | KEGG1.1.5.4 |
| BioCyc Enzyme Link: | BioCyc 1.1.5.4 |
| ExPASy Enzyme Link: | ExPASy1.1.5.4 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.5.4 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.5.4 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.5.4 |
| IntEnz Enzyme Link: | IntEnz 1.1.5.4 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.5.4 |
| RHEA:46012 | (S)-malate + a quinone = a quinol + oxaloacetate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[C;H0;+0:3](-[*:4])-[C;H0;+0:5](=[O;H0;+0:6])-[C;H0;+0:7](-[*:8])=[C;H0;+0:9](-[*:10])-[C;H0;+0:11]-1=[O;H0;+0:12].[*:13]-[CH;+0:14](-[*:15])-[OH;+0:16]>>[*:13]-[C;H0;+0:14](-[*:15])=[O;H0;+0:16].[*:1]-[c;H0;+0:2]1:[c;H0;+0:11](-[OH;+0:12]):[c;H0;+0:9](-[*:10]):[c;H0;+0:7](-[*:8]):[c;H0;+0:5](-[OH;+0:6]):[c;H0;+0:3]:1-[*:4] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| FAD-dependent malate dehydrogenase, a phospholipid-requiring enzyme from Mycobacterium sp. strain Takeo. Purification and some properties. | Imai T | 1978 Mar 14 | 629992 |
| Variations in the pathways of malate oxidation and phosphorylation in different species of Mycobacteria. | Prasada Reddy TL, Suryanarayana Murthy P, Venkitasubramanian TA | 1975 Feb 17 | 234747 |
| Another unusual type of citric acid cycle enzyme in Helicobacter pylori: the malate:quinone oxidoreductase. | Kather B, Stingl K, van der Rest ME, Altendorf K, Molenaar D | 2000 Jun | 10809701 |
| Biochemical and genetic characterization of the membrane-associated malate dehydrogenase (acceptor) from Corynebacterium glutamicum. | Molenaar D, van der Rest ME, Petrović S | 1998 Jun 1 | 9660197 |
| RHEA:30095 | (S)-malate + a menaquinone = a menaquinol + oxaloacetate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[C;H0;+0:3](-[*:4])-[C;H0;+0:5](=[O;H0;+0:6])-[*:7](:[cH;+0:8]:[*:9]):[c;H0;+0:10](:[*:11])-[C;H0;+0:12]-1=[O;H0;+0:13].[*:14]-[CH;+0:15](-[*:16])-[OH;+0:17]>>[*:14]-[C;H0;+0:15](-[*:16])=[O;H0;+0:17].[*:1]-[c;H0;+0:2]1:[c;H0;+0:3](-[*:4]):[c;H0;+0:5](-[OH;+0:6]):[*:7](:[cH;+0:10]:[*:11]):[c;H0;+0:8](:[*:9]):[c;H0;+0:12]:1-[OH;+0:13] |
| Reaction |  |
| Core-to-Core |