Enzyme

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EC Tree
     1. Oxidoreductases
        1.10 Acting on diphenols and related substances as donors
            1.10.3 With oxygen as acceptor
ID:1.10.3.15
Description:Grixazone synthase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.10.3.15
BRENDA Enzyme Link: BRENDA 1.10.3.15
KEGG Enzyme Link: KEGG1.10.3.15
BioCyc Enzyme Link: BioCyc 1.10.3.15
ExPASy Enzyme Link: ExPASy1.10.3.15
EC2PDB Enzyme Link: EC2PDB 1.10.3.15
ExplorEnz Enzyme Link: ExplorEnz 1.10.3.15
PRIAM enzyme-specific profiles Link: PRIAM 1.10.3.15
IntEnz Enzyme Link: IntEnz 1.10.3.15
MEDLINE Enzyme Link: MEDLINE 1.10.3.15
MSA:

1.10.3.15;

Phylogenetic Tree:

1.10.3.15;

Uniprot:
M-CSA:
RHEA:41424 2 3-amino-4-hydroxybenzaldehyde + N-acetyl-L-cysteine + 2 O2 = formate + grixazone A + H(+) + 3 H2O
RULE(radius=1) [*:1]-[SH;+0:2].[*:3]=[CH;+0:4]-[c;H0;+0:5]1:[cH;+0:6]:[*:7]:[c;H0;+0:8](-[OH;+0:9]):[*:10]:[cH;+0:11]:1.[NH2;+0:12]-[*:13]:[*:14]-[OH;+0:15].[O;H0;+0:16]=[O;H0;+0:17].[O;H0;+0:18]=[O;H0;+0:19]>>[*:1]-[S;H0;+0:2]-[c;H0;+0:11]1:[*:10]:[c;H0;+0:8](=[O;H0;+0:9]):[*:7]:[c;H0;+0:6]2:[o;H0;+0:15]:[*:14]:[*:13]:[n;H0;+0:12]:[c;H0;+0:5]:1-2.[*:3]=[CH;+0:4]-[OH;+0:16].[OH2;+0:17].[OH2;+0:18].[OH2;+0:19]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Phenoxazinone synthase: what's in a name?Le Roes-Hill M, Goodwin C, Burton S2009 Apr19268377
Novel benzene ring biosynthesis from C(3) and C(4) primary metabolites by two enzymes.Suzuki H, Ohnishi Y, Furusho Y, Sakuda S, Horinouchi S2006 Dec 117003031

RHEA:41420 2 3-amino-4-hydroxybenzoate + H(+) + N-acetyl-L-cysteine + 2 O2 = CO2 + grixazone B + 4 H2O
RULE(radius=1) [*:1]-[SH;+0:2].[*:3]=[C;H0;+0:4](-[OH;+0:5])-[c;H0;+0:6]1:[cH;+0:7]:[*:8]:[c;H0;+0:9](-[OH;+0:10]):[*:11]:[cH;+0:12]:1.[H+;H0:13].[NH2;+0:14]-[*:15]:[*:16]-[OH;+0:17].[O;H0;+0:18]=[O;H0;+0:19].[O;H0;+0:20]=[O;H0;+0:21]>>[*:1]-[S;H0;+0:2]-[c;H0;+0:12]1:[*:11]:[c;H0;+0:9](=[O;H0;+0:10]):[*:8]:[c;H0;+0:7]2:[o;H0;+0:17]:[*:16]:[*:15]:[n;H0;+0:14]:[c;H0;+0:6]:1-2.[*:3]=[C;H0;+0:4]=[O;H0;+0:5].[OH2;+0:18].[OH2;+0:19].[OH2;+0:20].[OH2;+0:21]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Phenoxazinone synthase: what's in a name?Le Roes-Hill M, Goodwin C, Burton S2009 Apr19268377
Novel benzene ring biosynthesis from C(3) and C(4) primary metabolites by two enzymes.Suzuki H, Ohnishi Y, Furusho Y, Sakuda S, Horinouchi S2006 Dec 117003031