| EC Tree |
| 1. Oxidoreductases |
| 1.10 Acting on diphenols and related substances as donors |
| 1.10.3 With oxygen as acceptor |
| ID: | 1.10.3.15 |
|---|---|
| Description: | Grixazone synthase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.10.3.15 |
| BRENDA Enzyme Link: | BRENDA 1.10.3.15 |
| KEGG Enzyme Link: | KEGG1.10.3.15 |
| BioCyc Enzyme Link: | BioCyc 1.10.3.15 |
| ExPASy Enzyme Link: | ExPASy1.10.3.15 |
| EC2PDB Enzyme Link: | EC2PDB 1.10.3.15 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.10.3.15 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.10.3.15 |
| IntEnz Enzyme Link: | IntEnz 1.10.3.15 |
| MEDLINE Enzyme Link: | MEDLINE 1.10.3.15 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:41424 | 2 3-amino-4-hydroxybenzaldehyde + N-acetyl-L-cysteine + 2 O2 = formate + grixazone A + H(+) + 3 H2O |
| RULE(radius=1) | [*:1]-[SH;+0:2].[*:3]=[CH;+0:4]-[c;H0;+0:5]1:[cH;+0:6]:[*:7]:[c;H0;+0:8](-[OH;+0:9]):[*:10]:[cH;+0:11]:1.[NH2;+0:12]-[*:13]:[*:14]-[OH;+0:15].[O;H0;+0:16]=[O;H0;+0:17].[O;H0;+0:18]=[O;H0;+0:19]>>[*:1]-[S;H0;+0:2]-[c;H0;+0:11]1:[*:10]:[c;H0;+0:8](=[O;H0;+0:9]):[*:7]:[c;H0;+0:6]2:[o;H0;+0:15]:[*:14]:[*:13]:[n;H0;+0:12]:[c;H0;+0:5]:1-2.[*:3]=[CH;+0:4]-[OH;+0:16].[OH2;+0:17].[OH2;+0:18].[OH2;+0:19] |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Phenoxazinone synthase: what's in a name? | Le Roes-Hill M, Goodwin C, Burton S | 2009 Apr | 19268377 |
| Novel benzene ring biosynthesis from C(3) and C(4) primary metabolites by two enzymes. | Suzuki H, Ohnishi Y, Furusho Y, Sakuda S, Horinouchi S | 2006 Dec 1 | 17003031 |
| RHEA:41420 | 2 3-amino-4-hydroxybenzoate + H(+) + N-acetyl-L-cysteine + 2 O2 = CO2 + grixazone B + 4 H2O |
| RULE(radius=1) | [*:1]-[SH;+0:2].[*:3]=[C;H0;+0:4](-[OH;+0:5])-[c;H0;+0:6]1:[cH;+0:7]:[*:8]:[c;H0;+0:9](-[OH;+0:10]):[*:11]:[cH;+0:12]:1.[H+;H0:13].[NH2;+0:14]-[*:15]:[*:16]-[OH;+0:17].[O;H0;+0:18]=[O;H0;+0:19].[O;H0;+0:20]=[O;H0;+0:21]>>[*:1]-[S;H0;+0:2]-[c;H0;+0:12]1:[*:11]:[c;H0;+0:9](=[O;H0;+0:10]):[*:8]:[c;H0;+0:7]2:[o;H0;+0:17]:[*:16]:[*:15]:[n;H0;+0:14]:[c;H0;+0:6]:1-2.[*:3]=[C;H0;+0:4]=[O;H0;+0:5].[OH2;+0:18].[OH2;+0:19].[OH2;+0:20].[OH2;+0:21] |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Phenoxazinone synthase: what's in a name? | Le Roes-Hill M, Goodwin C, Burton S | 2009 Apr | 19268377 |
| Novel benzene ring biosynthesis from C(3) and C(4) primary metabolites by two enzymes. | Suzuki H, Ohnishi Y, Furusho Y, Sakuda S, Horinouchi S | 2006 Dec 1 | 17003031 |