Enzyme

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     1. Oxidoreductases
        1.11 Acting on a peroxide as acceptor
            1.11.1 Peroxidases
ID:1.11.1.14
Description:Lignin peroxidase.
Alternative Name: LiP.
Ligninase I.
Diarylpropane peroxidase.
Diarylpropane oxygenase.
Prosite: PDOC00394;
PDB:
PDBScop
Cath: 1.10.420.10; 1.10.520.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.11.1.14
BRENDA Enzyme Link: BRENDA 1.11.1.14
KEGG Enzyme Link: KEGG1.11.1.14
BioCyc Enzyme Link: BioCyc 1.11.1.14
ExPASy Enzyme Link: ExPASy1.11.1.14
EC2PDB Enzyme Link: EC2PDB 1.11.1.14
ExplorEnz Enzyme Link: ExplorEnz 1.11.1.14
PRIAM enzyme-specific profiles Link: PRIAM 1.11.1.14
IntEnz Enzyme Link: IntEnz 1.11.1.14
MEDLINE Enzyme Link: MEDLINE 1.11.1.14
MSA:

1.11.1.14;

Phylogenetic Tree:

1.11.1.14;

Uniprot:
M-CSA:
RHEA:48004 1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol + H2O2 = 3,4-dimethoxybenzaldehyde + glycolaldehyde + guaiacol + H2O
RULE(radius=1) [*:1]-[CH;+0:2](-[OH;+0:3])-[CH;+0:4](-[CH2;+0:5]-[OH;+0:6])-[O;H0;+0:7]-[*:8].[OH;+0:9]-[OH;+0:10]>>[*:1]-[CH;+0:2]=[O;H0;+0:3].[*:8]-[OH;+0:7].[O;H0;+0:6]=[CH;+0:5]-[CH2;+0:4]-[OH;+0:9].[OH2;+0:10]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Detection and characterization of the lignin peroxidase compound II-veratryl alcohol cation radical complex.Khindaria A, Nie G, Aust SD1997 Nov 189369491
Lignin-degrading enzymes.Pollegioni L, Tonin F, Rosini E2015 Apr25649492
Two substrate interaction sites in lignin peroxidase revealed by site-directed mutagenesis.Doyle WA, Blodig W, Veitch NC, Piontek K, Smith AT1998 Oct 279790672
Stabilization of the veratryl alcohol cation radical by lignin peroxidase.Khindaria A, Yamazaki I, Aust SD1996 May 218639588
Veratryl alcohol oxidation by lignin peroxidase.Khindaria A, Yamazaki I, Aust SD1995 Dec 268527462
Characterization of the oxycomplex of lignin peroxidases from Phanerochaete chrysosporium: equilibrium and kinetics studies.Cai DY, Tien M1990 Feb 272328240
Lignin peroxidase compounds II and III. Spectral and kinetic characterization of reactions with peroxides.Wariishi H, Marquez L, Dunford HB, Gold MH1990 Jul 52162833

RHEA:30271 2 (3,4-dimethoxyphenyl)methanol + H2O2 = 2 (3,4-dimethoxyphenyl)methanol radical + 2 H2O
RULE(radius=1) [OH;+0:1]-[OH;+0:2]>>[OH2;+0:1].[OH2;+0:2]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Detection and characterization of the lignin peroxidase compound II-veratryl alcohol cation radical complex.Khindaria A, Nie G, Aust SD1997 Nov 189369491
Two substrate interaction sites in lignin peroxidase revealed by site-directed mutagenesis.Doyle WA, Blodig W, Veitch NC, Piontek K, Smith AT1998 Oct 279790672
Stabilization of the veratryl alcohol cation radical by lignin peroxidase.Khindaria A, Yamazaki I, Aust SD1996 May 218639588
Veratryl alcohol oxidation by lignin peroxidase.Khindaria A, Yamazaki I, Aust SD1995 Dec 268527462
Characterization of the oxycomplex of lignin peroxidases from Phanerochaete chrysosporium: equilibrium and kinetics studies.Cai DY, Tien M1990 Feb 272328240
Lignin peroxidase compounds II and III. Spectral and kinetic characterization of reactions with peroxides.Wariishi H, Marquez L, Dunford HB, Gold MH1990 Jul 52162833