Enzyme

Download
EC Tree
     1. Oxidoreductases
        1.12 Acting on hydrogen as donor
            1.12.98 With other, known, physiological acceptors
ID:1.12.98.1
Description:Coenzyme F420 hydrogenase.
Alternative Name: F420-reducing hydrogenase.
Coenzyme F420-dependent hydrogenase.
8-hydroxy-5-deazaflavin-reducing hydrogenase.
Cath: 1.10.645.10; 3.30.70.20; 3.40.50.700; 2.30.30.10; 2.30.30.1030;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.12.98.1
BRENDA Enzyme Link: BRENDA 1.12.98.1
KEGG Enzyme Link: KEGG1.12.98.1
BioCyc Enzyme Link: BioCyc 1.12.98.1
ExPASy Enzyme Link: ExPASy1.12.98.1
EC2PDB Enzyme Link: EC2PDB 1.12.98.1
ExplorEnz Enzyme Link: ExplorEnz 1.12.98.1
PRIAM enzyme-specific profiles Link: PRIAM 1.12.98.1
IntEnz Enzyme Link: IntEnz 1.12.98.1
MEDLINE Enzyme Link: MEDLINE 1.12.98.1
MSA:

1.12.98.1;

Phylogenetic Tree:

1.12.98.1;

Uniprot:
M-CSA:
RHEA:23760 H(+) + H2 + oxidized coenzyme F420-(gamma-Glu)(n) = reduced coenzyme F420-(gamma-Glu)(n)
RULE(radius=1) [*:1]-[n;H0;+0:2]1:[*:3]:[*:4]:[cH;+0:5]:[c;H0;+0:6](:[*:7])-[c;H0;+0:8]:1:[n;H0;+0:9]:[*:10].[H+;H0:11].[H;H0;+0:12]-[H;H0;+0:13]>>[*:1]-[N;H0;+0:2]1-[*:3]:[*:4]-[CH2;+0:5]-[c;H0;+0:6](:[*:7]):[c;H0;+0:8]-1:[nH;+0:9]:[*:10]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Hydrogenase.Adams MW, Mortenson LE, Chen JS1980 Dec6786341
A selenium-containing hydrogenase from Methanococcus vannielii. Identification of the selenium moiety as a selenocysteine residue.Yamazaki S1982 Jul 256211447
8-Hydroxy-5-deazaflavin-reducing hydrogenase from Methanobacterium thermoautotrophicum: 1. Purification and characterization.Fox JA, Livingston DJ, Orme-Johnson WH, Walsh CT1987 Jul 143663585
Purification and characterization of an 8-hydroxy-5-deazaflavin-reducing hydrogenase from the archaebacterium Methanococcus voltae.Muth E, Mörschel E, Klein A1987 Dec 153121317
Purification and properties of the membrane-associated coenzyme F420-reducing hydrogenase from Methanobacterium formicicum.Baron SF, Ferry JG1989 Jul2738024