| EC Tree |
| 1. Oxidoreductases |
| 1.12 Acting on hydrogen as donor |
| 1.12.98 With other, known, physiological acceptors |
| ID: | 1.12.98.1 |
|---|---|
| Description: | Coenzyme F420 hydrogenase. |
| Alternative Name: |
F420-reducing hydrogenase. Coenzyme F420-dependent hydrogenase. 8-hydroxy-5-deazaflavin-reducing hydrogenase. |
| Cath: | 1.10.645.10; 3.30.70.20; 3.40.50.700; 2.30.30.10; 2.30.30.1030; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.12.98.1 |
| BRENDA Enzyme Link: | BRENDA 1.12.98.1 |
| KEGG Enzyme Link: | KEGG1.12.98.1 |
| BioCyc Enzyme Link: | BioCyc 1.12.98.1 |
| ExPASy Enzyme Link: | ExPASy1.12.98.1 |
| EC2PDB Enzyme Link: | EC2PDB 1.12.98.1 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.12.98.1 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.12.98.1 |
| IntEnz Enzyme Link: | IntEnz 1.12.98.1 |
| MEDLINE Enzyme Link: | MEDLINE 1.12.98.1 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:23760 | H(+) + H2 + oxidized coenzyme F420-(gamma-Glu)(n) = reduced coenzyme F420-(gamma-Glu)(n) |
| RULE(radius=1) | [*:1]-[n;H0;+0:2]1:[*:3]:[*:4]:[cH;+0:5]:[c;H0;+0:6](:[*:7])-[c;H0;+0:8]:1:[n;H0;+0:9]:[*:10].[H+;H0:11].[H;H0;+0:12]-[H;H0;+0:13]>>[*:1]-[N;H0;+0:2]1-[*:3]:[*:4]-[CH2;+0:5]-[c;H0;+0:6](:[*:7]):[c;H0;+0:8]-1:[nH;+0:9]:[*:10] |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Hydrogenase. | Adams MW, Mortenson LE, Chen JS | 1980 Dec | 6786341 |
| A selenium-containing hydrogenase from Methanococcus vannielii. Identification of the selenium moiety as a selenocysteine residue. | Yamazaki S | 1982 Jul 25 | 6211447 |
| 8-Hydroxy-5-deazaflavin-reducing hydrogenase from Methanobacterium thermoautotrophicum: 1. Purification and characterization. | Fox JA, Livingston DJ, Orme-Johnson WH, Walsh CT | 1987 Jul 14 | 3663585 |
| Purification and characterization of an 8-hydroxy-5-deazaflavin-reducing hydrogenase from the archaebacterium Methanococcus voltae. | Muth E, Mörschel E, Klein A | 1987 Dec 15 | 3121317 |
| Purification and properties of the membrane-associated coenzyme F420-reducing hydrogenase from Methanobacterium formicicum. | Baron SF, Ferry JG | 1989 Jul | 2738024 |