EC number:1.13.11.63
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) |
| 1.13.11 With incorporation of two atoms of oxygen |
| ID: | 1.13.11.63 |
|---|---|
| Description: | Beta-carotene 15,15'-dioxygenase. |
| Alternative Name: |
Carotene dioxygenase. Carotene 15,15'-dioxygenase. Beta-carotene 15,15'-monooxygenase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.13.11.63 |
| BRENDA Enzyme Link: | BRENDA 1.13.11.63 |
| KEGG Enzyme Link: | KEGG1.13.11.63 |
| BioCyc Enzyme Link: | BioCyc 1.13.11.63 |
| ExPASy Enzyme Link: | ExPASy1.13.11.63 |
| EC2PDB Enzyme Link: | EC2PDB 1.13.11.63 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.13.11.63 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.13.11.63 |
| IntEnz Enzyme Link: | IntEnz 1.13.11.63 |
| MEDLINE Enzyme Link: | MEDLINE 1.13.11.63 |
EC number:1.13.11.63
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:32887 | all-trans-beta-carotene + O2 = 2 all-trans-retinal |
| RULE(radius=1) | [*:1]-[CH;+0:2]=[CH;+0:3]-[*:4].[O;H0;+0:5]=[O;H0;+0:6]>>[*:4]-[CH;+0:3]=[O;H0;+0:5].[*:1]-[CH;+0:2]=[O;H0;+0:6] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The human enzyme that converts dietary provitamin A carotenoids to vitamin A is a dioxygenase. | dela Seña C, Riedl KM, Narayanasamy S, Curley RW Jr, Schwartz SJ, Harrison EH | 2014 May 9 | 24668807 |
| Substrate specificity of purified recombinant human β-carotene 15,15'-oxygenase (BCO1). | dela Seña C, Narayanasamy S, Riedl KM, Curley RW Jr, Schwartz SJ, Harrison EH | 2013 Dec 27 | 24187135 |
| Retinal production from beta-carotene by beta-carotene 15,15'-dioxygenase from an unculturable marine bacterium. | Kim YS, Park CS, Oh DK | 2010 Jul | 20229064 |
| In vitro characterization of a recombinant Blh protein from an uncultured marine bacterium as a beta-carotene 15,15'-dioxygenase. | Kim YS, Kim NH, Yeom SJ, Kim SW, Oh DK | 2009 Jun 5 | 19366683 |
| Substrate specificity of a recombinant chicken beta-carotene 15,15'-monooxygenase that converts beta-carotene into retinal. | Kim YS, Oh DK | 2009 Mar | 18979213 |