EC Tree |
1. Oxidoreductases |
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) |
1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases) |
ID: | 1.13.12.6 |
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Description: | Cypridina-luciferin 2-monooxygenase. |
Alternative Name: |
Luciferase. Cypridina-type luciferase. |
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Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 1.13.12.6 |
BRENDA Enzyme Link: | BRENDA 1.13.12.6 |
KEGG Enzyme Link: | KEGG1.13.12.6 |
BioCyc Enzyme Link: | BioCyc 1.13.12.6 |
ExPASy Enzyme Link: | ExPASy1.13.12.6 |
EC2PDB Enzyme Link: | EC2PDB 1.13.12.6 |
ExplorEnz Enzyme Link: | ExplorEnz 1.13.12.6 |
PRIAM enzyme-specific profiles Link: | PRIAM 1.13.12.6 |
IntEnz Enzyme Link: | IntEnz 1.13.12.6 |
MEDLINE Enzyme Link: | MEDLINE 1.13.12.6 |
MSA: | |
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Phylogenetic Tree: | |
Uniprot: | |
M-CSA: |
RHEA:22760 | Cypridina luciferin + O2 = CO2 + hnu + oxidized Cypridina luciferin |
RULE(radius=1) | [*:1]=[c;H0;+0:2]1:[c;H0;+0:3](-[CH;+0:4](-[*:5])-[CH2;+0:6]-[CH3;+0:7]):[n;H0;+0:8]:[c;H0;+0:9]2:[*:10]:[nH;+0:11]:[*:12]:[cH;+0:13]:[n;H0;+0:14]:1-2.[O;H0;+0:15]=[O;H0;+0:16]>>[*:1]=[C;H0;+0:2](-[NH;+0:14]-[c;H0;+0:9]1:[*:10]:[n;H0;+0:11]:[*:12]:[cH;+0:13]:[n;H0;+0:8]:1)-[CH;+0:3](-[CH3;+0:7])-[CH2;+0:4]-[*:5].[O;H0;+0:15]=[C;H0;+0:6]=[O;H0;+0:16] |
Reaction | ![]() |
Core-to-Core |
Title | Authors | Date | PubMed ID |
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Mechanism of the enzyme--catalyzed oxidation of Cypridina and firefly luciferins studied by means of 17O2 and H218O1. | Tsuji FI, DeLuca M, Boyer PD, Endo S, Akutagawa M | 1977 Jan 24 | 836314 |
Some properties of luciferase from the bioluminescent crustacean, Cypridina hilgendorfii. | Tsuji FI, Lynch RV 3rd, Stevens CL | 1974 Dec 3 | 4433517 |
Cloning and expression of cDNA for the luciferase from the marine ostracod Vargula hilgendorfii. | Thompson EM, Nagata S, Tsuji FI | 1989 Sep | 2771943 |