EC number:1.14.11.10
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor |
| ID: | 1.14.11.10 |
|---|---|
| Description: | Pyrimidine-deoxynucleoside 1'-dioxygenase. |
| Alternative Name: |
Pyrimidine-deoxynucleoside,2-oxoglutarate 1'-dioxygenase. Deoxyuridine-uridine 1'-dioxygenase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.11.10 |
| BRENDA Enzyme Link: | BRENDA 1.14.11.10 |
| KEGG Enzyme Link: | KEGG1.14.11.10 |
| BioCyc Enzyme Link: | BioCyc 1.14.11.10 |
| ExPASy Enzyme Link: | ExPASy1.14.11.10 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.11.10 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.11.10 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.11.10 |
| IntEnz Enzyme Link: | IntEnz 1.14.11.10 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.11.10 |
EC number:1.14.11.10
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:23316 | 2'-deoxyuridine + 2-oxoglutarate + O2 = 2-deoxy-D-ribono-1,4-lactone + CO2 + succinate + uracil |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[n;H0;+0:4](:[*:5]):[*:6].[*:7]=[C;H0;+0:8](-[OH;+0:9])-[C;H0;+0:10](=[*:11])-[*:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:13].[*:5]:[nH;+0:4]:[*:6].[*:11]=[C;H0;+0:10](-[*:12])-[OH;+0:14].[*:7]=[C;H0;+0:8]=[O;H0;+0:9] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Identification of two alpha-ketoglutarate-dependent dioxygenases in extracts of Rhodotorula glutinis catalyzing deoxyuridine hydroxylation. | Stubbe J | 1985 Aug 25 | 4040518 |