EC number:1.14.12.10

Enzyme

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EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
ID:1.14.12.10
Description:Benzoate 1,2-dioxygenase.
Alternative Name: Benzoic hydroxylase.
Benzoate hydroxylase.
Prosite: PDOC00493;
PDB:
PDBScop
Cath: 3.10.450.50;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.12.10
BRENDA Enzyme Link: BRENDA 1.14.12.10
KEGG Enzyme Link: KEGG1.14.12.10
BioCyc Enzyme Link: BioCyc 1.14.12.10
ExPASy Enzyme Link: ExPASy1.14.12.10
EC2PDB Enzyme Link: EC2PDB 1.14.12.10
ExplorEnz Enzyme Link: ExplorEnz 1.14.12.10
PRIAM enzyme-specific profiles Link: PRIAM 1.14.12.10
IntEnz Enzyme Link: IntEnz 1.14.12.10
MEDLINE Enzyme Link: MEDLINE 1.14.12.10

EC number:1.14.12.10

MSA:

1.14.12.10;
Phylogenetic Tree:

1.14.12.10;
Uniprot:
M-CSA:
RHEA:12633 benzoate + H(+) + NADH + O2 = (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+)
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]-[c;H0;+0:10]1:[cH;+0:11]:[cH;+0:12]:[cH;+0:13]:[cH;+0:14]:[cH;+0:15]:1.[H+;H0:16].[O;H0;+0:17]=[O;H0;+0:18]>>[*:9]-[C;H0;+0:10]1(-[OH;+0:17])-[CH;+0:15]=[CH;+0:14]-[CH;+0:13]=[CH;+0:12]-[CH;+0:11]-1-[OH;+0:18].[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1
Reaction
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References

TitleAuthorsDatePubMed ID
Potential DNA slippage structures acquired during evolutionary divergence of Acinetobacter calcoaceticus chromosomal benABC and Pseudomonas putida TOL pWW0 plasmid xylXYZ, genes encoding benzoate dioxygenases.Harayama S, Rekik M, Bairoch A, Neidle EL, Ornston LN1991 Dec1938949