EC number:1.14.12.14

Enzyme

Download
EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
ID:1.14.12.14
Description:2-aminobenzenesulfonate 2,3-dioxygenase.
Alternative Name: 2-aminosulfobenzene 2,3-dioxygenase.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.12.14
BRENDA Enzyme Link: BRENDA 1.14.12.14
KEGG Enzyme Link: KEGG1.14.12.14
BioCyc Enzyme Link: BioCyc 1.14.12.14
ExPASy Enzyme Link: ExPASy1.14.12.14
EC2PDB Enzyme Link: EC2PDB 1.14.12.14
ExplorEnz Enzyme Link: ExplorEnz 1.14.12.14
PRIAM enzyme-specific profiles Link: PRIAM 1.14.12.14
IntEnz Enzyme Link: IntEnz 1.14.12.14
MEDLINE Enzyme Link: MEDLINE 1.14.12.14

EC number:1.14.12.14

MSA:

1.14.12.14;
Phylogenetic Tree:

1.14.12.14;
Uniprot:
M-CSA:
RHEA:23468 2-aminobenzenesulfonate + 2 H(+) + NADH + O2 = 2,3-dihydroxybenzenesulfonate + NAD(+) + NH4(+)
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]:[c;H0;+0:10](-[NH2;+0:11]):[cH;+0:12]:[*:13].[H+;H0:14].[H+;H0:15].[O;H0;+0:16]=[O;H0;+0:17]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]:[c;H0;+0:10](-[OH;+0:17]):[c;H0;+0:12](:[*:13])-[OH;+0:16].[NH3;+0:11]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
3-Sulphocatechol 2,3-dioxygenase and other dioxygenases (EC 1.13.11.2 and EC 1.14.12.-) in the degradative pathways of 2-aminobenzenesulphonic, benzenesulphonic and 4-toluenesulphonic acids in Alcaligenes sp. strain O-1.Junker F, Leisinger T, Cook AM1994 Jul8075807
Oxygenation and spontaneous deamination of 2-aminobenzenesulphonic acid in Alcaligenes sp. strain O-1 with subsequent meta ring cleavage and spontaneous desulphonation to 2-hydroxymuconic acid.Junker F, Field JA, Bangerter F, Ramsteiner K, Kohler HP, Joannou CL, Mason JR, Leisinger T, Cook AM1994 Jun 18002948