EC number:1.14.12.15
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor |
| ID: | 1.14.12.15 |
|---|---|
| Description: | Terephthalate 1,2-dioxygenase. |
| Alternative Name: |
Benzene-1,4-dicarboxylate 1,2-dioxygenase. 1,4-dicarboxybenzoate 1,2-dioxygenase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.12.15 |
| BRENDA Enzyme Link: | BRENDA 1.14.12.15 |
| KEGG Enzyme Link: | KEGG1.14.12.15 |
| BioCyc Enzyme Link: | BioCyc 1.14.12.15 |
| ExPASy Enzyme Link: | ExPASy1.14.12.15 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.12.15 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.12.15 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.12.15 |
| IntEnz Enzyme Link: | IntEnz 1.14.12.15 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.12.15 |
EC number:1.14.12.15
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:10312 | H(+) + NADH + O2 + terephthalate = (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+) |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]-[c;H0;+0:10]1:[cH;+0:11]:[cH;+0:12]:[c;H0;+0:13](-[*:14]):[cH;+0:15]:[cH;+0:16]:1.[H+;H0:17].[O;H0;+0:18]=[O;H0;+0:19]>>[*:9]-[C;H0;+0:10]1=[CH;+0:11]-[CH;+0:12](-[OH;+0:19])-[C;H0;+0:13](-[*:14])(-[OH;+0:18])-[CH;+0:15]=[CH;+0:16]-1.[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Terephthalate 1,2-dioxygenase system from Comamonas testosteroni T-2: purification and some properties of the oxygenase component. | Schläfli HR, Weiss MA, Leisinger T, Cook AM | 1994 Nov | 7961417 |
| Enzymatic properties of terephthalate 1,2-dioxygenase of Comamonas sp. strain E6. | Fukuhara Y, Kasai D, Katayama Y, Fukuda M, Masai E | 2008 Sep | 18776687 |