EC number:1.14.12.22
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor |
| ID: | 1.14.12.22 |
|---|---|
| Description: | Carbazole 1,9a-dioxygenase. |
| Alternative Name: |
CARDO. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.12.22 |
| BRENDA Enzyme Link: | BRENDA 1.14.12.22 |
| KEGG Enzyme Link: | KEGG1.14.12.22 |
| BioCyc Enzyme Link: | BioCyc 1.14.12.22 |
| ExPASy Enzyme Link: | ExPASy1.14.12.22 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.12.22 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.12.22 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.12.22 |
| IntEnz Enzyme Link: | IntEnz 1.14.12.22 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.12.22 |
EC number:1.14.12.22
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:27842 | 9H-carbazole + H(+) + NADPH + O2 = 2'-aminobiphenyl-2,3-diol + NADP(+) |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]:[c;H0;+0:10]1:[*:11]:[nH;+0:12]:[c;H0;+0:13](:[cH;+0:14]:[*:15]):[c;H0;+0:16]:1:[*:17].[H+;H0:18].[O;H0;+0:19]=[O;H0;+0:20]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]:[c;H0;+0:10](:[*:11]-[NH2;+0:12])-[c;H0;+0:16](:[*:17]):[c;H0;+0:13](-[OH;+0:20]):[c;H0;+0:14](:[*:15])-[OH;+0:19] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The genes coding for the conversion of carbazole to catechol are flanked by IS6100 elements in Sphingomonas sp. strain XLDN2-5. | Gai Z, Wang X, Liu X, Tai C, Tang H, He X, Wu G, Deng Z, Xu P | 2010 Apr 2 | 20368802 |
| Purification and characterization of carbazole 1,9a-dioxygenase, a three-component dioxygenase system of Pseudomonas resinovorans strain CA10. | Nam JW, Nojiri H, Noguchi H, Uchimura H, Yoshida T, Habe H, Yamane H, Omori T | 2002 Dec | 12450807 |
| RHEA:27838 | 9H-carbazole + H(+) + NADH + O2 = 2'-aminobiphenyl-2,3-diol + NAD(+) |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]:[c;H0;+0:10]1:[*:11]:[nH;+0:12]:[c;H0;+0:13](:[cH;+0:14]:[*:15]):[c;H0;+0:16]:1:[*:17].[H+;H0:18].[O;H0;+0:19]=[O;H0;+0:20]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]:[c;H0;+0:10](:[*:11]-[NH2;+0:12])-[c;H0;+0:16](:[*:17]):[c;H0;+0:13](-[OH;+0:20]):[c;H0;+0:14](:[*:15])-[OH;+0:19] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The genes coding for the conversion of carbazole to catechol are flanked by IS6100 elements in Sphingomonas sp. strain XLDN2-5. | Gai Z, Wang X, Liu X, Tai C, Tang H, He X, Wu G, Deng Z, Xu P | 2010 Apr 2 | 20368802 |
| Purification and characterization of carbazole 1,9a-dioxygenase, a three-component dioxygenase system of Pseudomonas resinovorans strain CA10. | Nam JW, Nojiri H, Noguchi H, Uchimura H, Yoshida T, Habe H, Yamane H, Omori T | 2002 Dec | 12450807 |