EC number:1.14.12.23
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor |
| ID: | 1.14.12.23 |
|---|---|
| Description: | Nitroarene dioxygenase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.12.23 |
| BRENDA Enzyme Link: | BRENDA 1.14.12.23 |
| KEGG Enzyme Link: | KEGG1.14.12.23 |
| BioCyc Enzyme Link: | BioCyc 1.14.12.23 |
| ExPASy Enzyme Link: | ExPASy1.14.12.23 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.12.23 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.12.23 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.12.23 |
| IntEnz Enzyme Link: | IntEnz 1.14.12.23 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.12.23 |
EC number:1.14.12.23
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:46508 | NADH + nitrobenzene + O2 = catechol + NAD(+) + nitrite |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]=[N+;H0:10](-[*:11])-[c;H0;+0:12](:[*:13]):[cH;+0:14]:[*:15].[O;H0;+0:16]=[O;H0;+0:17]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:13]:[c;H0;+0:12](-[OH;+0:16]):[c;H0;+0:14](:[*:15])-[OH;+0:17].[*:9]=[N;H0;+0:10]-[*:11] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Enzyme specificity of 2-nitrotoluene 2,3-dioxygenase from Pseudomonas sp. strain JS42 is determined by the C-terminal region of the alpha subunit of the oxygenase component. | Parales JV, Parales RE, Resnick SM, Gibson DT | 1998 Mar | 9495758 |
| Expression, purification and substrate specificities of 3-nitrotoluene dioxygenase from Diaphorobacter sp. strain DS2. | Singh D, Kumari A, Ramaswamy S, Ramanathan G | 2014 Feb 28 | 24491551 |
| Patchwork assembly of nag-like nitroarene dioxygenase genes and the 3-chlorocatechol degradation cluster for evolution of the 2-chloronitrobenzene catabolism pathway in Pseudomonas stutzeri ZWLR2-1. | Liu H, Wang SJ, Zhang JJ, Dai H, Tang H, Zhou NY | 2011 Jul | 21602392 |
| Molecular characterization and substrate specificity of nitrobenzene dioxygenase from Comamonas sp. strain JS765. | Lessner DJ, Johnson GR, Parales RE, Spain JC, Gibson DT | 2002 Feb | 11823201 |