EC number:1.14.12.24
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor |
| ID: | 1.14.12.24 |
|---|---|
| Description: | 2,4-dinitrotoluene dioxygenase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.12.24 |
| BRENDA Enzyme Link: | BRENDA 1.14.12.24 |
| KEGG Enzyme Link: | KEGG1.14.12.24 |
| BioCyc Enzyme Link: | BioCyc 1.14.12.24 |
| ExPASy Enzyme Link: | ExPASy1.14.12.24 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.12.24 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.12.24 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.12.24 |
| IntEnz Enzyme Link: | IntEnz 1.14.12.24 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.12.24 |
EC number:1.14.12.24
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:46760 | 2,4-dinitrotoluene + NADH + O2 = 4-methyl-5-nitrocatechol + NAD(+) + nitrite |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]=[N+;H0:10](-[*:11])-[c;H0;+0:12](:[*:13]):[cH;+0:14]:[*:15].[O;H0;+0:16]=[O;H0;+0:17]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:15]:[c;H0;+0:14](-[OH;+0:17]):[c;H0;+0:12](:[*:13])-[OH;+0:16].[*:9]=[N;H0;+0:10]-[*:11] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| 2,4-Dinitrotoluene dioxygenase from Burkholderia sp. strain DNT: similarity to naphthalene dioxygenase. | Suen WC, Haigler BE, Spain JC | 1996 Aug | 8759857 |