EC number:1.14.12.3

Enzyme

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EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
ID:1.14.12.3
Description:Benzene 1,2-dioxygenase.
Alternative Name: Benzene hydroxylase.
Prosite: PDOC00493;
PDB:
PDBScop
1NDO 8031710; 8044088; 8031710; 8044088; 8031707; 8031709; 8044085; 8044087; 8031710; 8044088; 8031707; 8031709; 8044085; 8044087; 8031707; 8031709; 8044085; 8044087;
1UUW 8031710; 8044088; 8031707; 8031709; 8044085; 8044087;
1O7W 8031710; 8044088; 8031707; 8031709; 8044085; 8044087;
1O7M 8031710; 8044088; 8031707; 8031709; 8044085; 8044087;
1O7H 8031710; 8044088; 8031707; 8031709; 8044085; 8044087;
 » show all
Cath: 3.10.450.50; 3.90.380.10; 2.102.10.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.12.3
BRENDA Enzyme Link: BRENDA 1.14.12.3
KEGG Enzyme Link: KEGG1.14.12.3
BioCyc Enzyme Link: BioCyc 1.14.12.3
ExPASy Enzyme Link: ExPASy1.14.12.3
EC2PDB Enzyme Link: EC2PDB 1.14.12.3
ExplorEnz Enzyme Link: ExplorEnz 1.14.12.3
PRIAM enzyme-specific profiles Link: PRIAM 1.14.12.3
IntEnz Enzyme Link: IntEnz 1.14.12.3
MEDLINE Enzyme Link: MEDLINE 1.14.12.3

EC number:1.14.12.3

MSA:

1.14.12.3;
Phylogenetic Tree:

1.14.12.3;
Uniprot:
M-CSA:
RHEA:13813 benzene + H(+) + NADH + O2 = cis-1,2-dihydrobenzene-1,2-diol + NAD(+)
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[H+;H0:9].[O;H0;+0:10]=[O;H0;+0:11].[cH;+0:12]1:[cH;+0:13]:[cH;+0:14]:[cH;+0:15]:[cH;+0:16]:[cH;+0:17]:1>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[OH;+0:10]-[CH;+0:12]1-[CH;+0:17]=[CH;+0:16]-[CH;+0:15]=[CH;+0:14]-[CH;+0:13]-1-[OH;+0:11]
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References

TitleAuthorsDatePubMed ID
Structures of the multicomponent Rieske non-heme iron toluene 2,3-dioxygenase enzyme system.Friemann R, Lee K, Brown EN, Gibson DT, Eklund H, Ramaswamy S2009 Jan19153463