EC number:1.14.13.1
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.13.1 |
|---|---|
| Description: | Salicylate 1-monooxygenase. |
| Alternative Name: |
Salicylic hydroxylase. Salicylate hydroxylase. |
| Cath: | 3.30.9.30; 3.50.50.60; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.13.1 |
| BRENDA Enzyme Link: | BRENDA 1.14.13.1 |
| KEGG Enzyme Link: | KEGG1.14.13.1 |
| BioCyc Enzyme Link: | BioCyc 1.14.13.1 |
| ExPASy Enzyme Link: | ExPASy1.14.13.1 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.13.1 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.13.1 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.13.1 |
| IntEnz Enzyme Link: | IntEnz 1.14.13.1 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.13.1 |
EC number:1.14.13.1
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:11004 | 2 H(+) + NADH + O2 + salicylate = catechol + CO2 + H2O + NAD(+) |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]=[C;H0;+0:10](-[OH;+0:11])-[c;H0;+0:12](:[*:13]):[*:14].[H+;H0:15].[H+;H0:16].[O;H0;+0:17]=[O;H0;+0:18]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:13]:[c;H0;+0:12](:[*:14])-[OH;+0:17].[*:9]=[C;H0;+0:10]=[O;H0;+0:11].[OH2;+0:18] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Terbinafine resistance mediated by salicylate 1-monooxygenase in Aspergillus nidulans. | Graminha MA, Rocha EM, Prade RA, Martinez-Rossi NM | 2004 Sep | 15328121 |