EC number:1.14.13.105
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.13.105 |
|---|---|
| Description: | Monocyclic monoterpene ketone monooxygenase. |
| Alternative Name: |
MMKMO. Dihydrocarvone 1,2-monooxygenase. 1-hydroxy-2-oxolimonene 1,2-monooxygenase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.13.105 |
| BRENDA Enzyme Link: | BRENDA 1.14.13.105 |
| KEGG Enzyme Link: | KEGG1.14.13.105 |
| BioCyc Enzyme Link: | BioCyc 1.14.13.105 |
| ExPASy Enzyme Link: | ExPASy1.14.13.105 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.13.105 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.13.105 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.13.105 |
| IntEnz Enzyme Link: | IntEnz 1.14.13.105 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.13.105 |
EC number:1.14.13.105
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:32431 | (1R,4S)-menthone + H(+) + NADPH + O2 = (4R,7S)-7-isopropyl-4-methyloxepan-2-one + H2O + NADP(+) |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[C;H0;+0:4](=[*:5])-[*:6].[*:7]-[N;H0;+0:8]1-[CH;+0:9]=[C;H0;+0:10](-[*:11])-[CH2;+0:12]-[CH;+0:13]=[CH;+0:14]-1.[H+;H0:15].[O;H0;+0:16]=[O;H0;+0:17]>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:17]-[C;H0;+0:4](=[*:5])-[*:6].[*:7]-[n+;H0:8]1:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:[cH;+0:13]:[cH;+0:14]:1.[OH2;+0:16] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Biocatalytic Characterization of Human FMO5: Unearthing Baeyer-Villiger Reactions in Humans. | Fiorentini F, Geier M, Binda C, Winkler M, Faber K, Hall M, Mattevi A | 2016 Apr 15 | 26771671 |
| Metabolism of carveol and dihydrocarveol in Rhodococcus erythropolis DCL14. | van der Werf MJ, Boot AM | 2000 May | 10832640 |
| Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene. | van der Werf MJ, Swarts HJ, de Bont JA | 1999 May | 10224006 |
| Purification and characterization of a Baeyer-Villiger mono-oxygenase from Rhodococcus erythropolis DCL14 involved in three different monocyclic monoterpene degradation pathways. | Van Der Werf MJ | 2000 May 1 | 10769172 |
| RHEA:32435 | dihydrocarvone + H(+) + NADPH + O2 = 4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+) |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[C;H0;+0:4](=[*:5])-[*:6].[*:7]-[N;H0;+0:8]1-[CH;+0:9]=[C;H0;+0:10](-[*:11])-[CH2;+0:12]-[CH;+0:13]=[CH;+0:14]-1.[H+;H0:15].[O;H0;+0:16]=[O;H0;+0:17]>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:17]-[C;H0;+0:4](=[*:5])-[*:6].[*:7]-[n+;H0:8]1:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:[cH;+0:13]:[cH;+0:14]:1.[OH2;+0:16] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Metabolism of carveol and dihydrocarveol in Rhodococcus erythropolis DCL14. | van der Werf MJ, Boot AM | 2000 May | 10832640 |
| Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene. | van der Werf MJ, Swarts HJ, de Bont JA | 1999 May | 10224006 |
| Purification and characterization of a Baeyer-Villiger mono-oxygenase from Rhodococcus erythropolis DCL14 involved in three different monocyclic monoterpene degradation pathways. | Van Der Werf MJ | 2000 May 1 | 10769172 |
| RHEA:32583 | dihydrocarvone + H(+) + NADPH + O2 = 6-isopropenyl-3-methyloxepan-2-one + H2O + NADP(+) |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]=[C;H0;+0:10](-[*:11])-[CH2;+0:12]-[*:13].[H+;H0:14].[O;H0;+0:15]=[O;H0;+0:16]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]=[C;H0;+0:10](-[*:11])-[O;H0;+0:16]-[CH2;+0:12]-[*:13].[OH2;+0:15] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Metabolism of carveol and dihydrocarveol in Rhodococcus erythropolis DCL14. | van der Werf MJ, Boot AM | 2000 May | 10832640 |
| Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene. | van der Werf MJ, Swarts HJ, de Bont JA | 1999 May | 10224006 |
| Purification and characterization of a Baeyer-Villiger mono-oxygenase from Rhodococcus erythropolis DCL14 involved in three different monocyclic monoterpene degradation pathways. | Van Der Werf MJ | 2000 May 1 | 10769172 |
| RHEA:55004 | 1-hydroxylimonen-2-one + NADPH + O2 = 3-isopropenyl-6-oxoheptanoate + H2O + NADP(+) |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]=[C;H0;+0:10](-[*:11])-[C;H0;+0:12](-[*:13])(-[*:14])-[OH;+0:15].[O;H0;+0:16]=[O;H0;+0:17]>>([*:13]-[C;H0;+0:12](-[*:14])=[O;H0;+0:15].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:16]).[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[OH2;+0:17] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene. | van der Werf MJ, Swarts HJ, de Bont JA | 1999 May | 10224006 |
| Purification and characterization of a Baeyer-Villiger mono-oxygenase from Rhodococcus erythropolis DCL14 involved in three different monocyclic monoterpene degradation pathways. | Van Der Werf MJ | 2000 May 1 | 10769172 |