Enzyme

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     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.13.111
Description:Methanesulfonate monooxygenase (NADH).
Alternative Name: MSAMO.
MSA monooxygenase.
Methanesulfonic acid monooxygenase.
Mesylate monooxygenase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.13.111
BRENDA Enzyme Link: BRENDA 1.14.13.111
KEGG Enzyme Link: KEGG1.14.13.111
BioCyc Enzyme Link: BioCyc 1.14.13.111
ExPASy Enzyme Link: ExPASy1.14.13.111
EC2PDB Enzyme Link: EC2PDB 1.14.13.111
ExplorEnz Enzyme Link: ExplorEnz 1.14.13.111
PRIAM enzyme-specific profiles Link: PRIAM 1.14.13.111
IntEnz Enzyme Link: IntEnz 1.14.13.111
MEDLINE Enzyme Link: MEDLINE 1.14.13.111
MSA:

1.14.13.111;

Phylogenetic Tree:

1.14.13.111;

Uniprot:
M-CSA:
RHEA:26077 methanesulfonate + NADH + O2 = formaldehyde + H2O + NAD(+) + sulfite
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]=[S;H0;+0:10](-[*:11])(-[CH3;+0:12])=[O;H0;+0:13].[O;H0;+0:14]=[O;H0;+0:15]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]=[S;H0;+0:10](-[*:11])-[OH;+0:13].[CH2;+0:12]=[O;H0;+0:14].[OH2;+0:15]
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References

TitleAuthorsDatePubMed ID
Metabolism of methanesulfonic acid involves a multicomponent monooxygenase enzyme.Higgins TP, Davey M, Trickett J, Kelly DP, Murrell JC1996 Feb8932698
Molecular analysis of a novel methanesulfonic acid monooxygenase from the methylotroph Methylosulfonomonas methylovora.de Marco P, Moradas-Ferreira P, Higgins TP, McDonald I, Kenna EM, Murrell JC1999 Apr10094704